CAJ | 학술논문

目的：探讨桂哌齐特治疗急性心肌梗死的临床疗效及对患者血清炎症因子的影响。方法将我院收治的118例急性心肌梗死患者随机分为对照组与观察组,其中对照组58例,观察组60例。对照组患者接受常规治疗,观察组患者在对照组治疗的基础上,同时接受桂哌齐特静点,疗程2周。比较两组的临床疗效、血流变学及血清炎症因子的改变。结果观察组显效率显著高于对照组(86．7% vs 70．7%,P<0．05)；观察组血流变学指标全血粘度、血浆粘度均显著优于对照组(P<0．05)；观察组血清超敏-C反应蛋白(hs-CRP)及白介素-6(IL-6)显著低于对照组(P<0．05)。结论桂哌齐特可显著降低急性心肌梗死患者血清炎症因子及血液粘滞度,对急性心肌梗死患者具有良好的临床治疗效果。
목적：탐토계고제특치료급성심기경사적림상료효급대환자혈청염증인자적영향。방법장아원수치적118례급성심기경사환자수궤분위대조조여관찰조,기중대조조58례,관찰조60례。대조조환자접수상규치료,관찰조환자재대조조치료적기출상,동시접수계고제특정점,료정2주。비교량조적림상료효、혈류변학급혈청염증인자적개변。결과관찰조현효솔현저고우대조조(86．7% vs 70．7%,P<0．05)；관찰조혈류변학지표전혈점도、혈장점도균현저우우대조조(P<0．05)；관찰조혈청초민-C반응단백(hs-CRP)급백개소-6(IL-6)현저저우대조조(P<0．05)。결론계고제특가현저강저급성심기경사환자혈청염증인자급혈액점체도,대급성심기경사환자구유량호적림상치료효과。
Objective To explore the clinical effect of cinepazide on acute myocardial infarction and the influ-ence on inflammatory factors. Methods 118 patients with acute myocardial infarction admitted to our hospital were randomly divided into control group and experience group,58 cases in control group and 60 cases in experience group. Control group was given routine treatment,and experience group received cinepazide treatment. The course of treatment was 2 weeks. Clinical effect,blood rheology and serum inflammatory factors of the two groups were compared. Results The efficiency rate in experience group was higher than that in control group (86. 7% vs 70. 7%,P<0. 05);Whole blood viscosity and plasma viscosity after treatment in experience group were superior to that in control group ( P <0. 05);hs-CRP and IL-6 in experience group were much lower than those in control group (P<0. 05). Conclusion Cinepazide treatment for acute myocardial infarction can obviously decrease serum inflammatory factors and blood vis-cosity,and has obvious effect on myocardial infarction patients.