CAJ | 학술논문

目的：探讨进行性核上性麻痹（PSP）的临床和影像学特点。方法回顾性分析12例临床诊断的PSP患者的临床和影像学资料。结果12例患者主要症状为运动迟缓、姿势不稳、假性球麻痹和垂直性眼肌麻痹，部分患者有认知功能障碍、小便障碍等。多数患者首发症状为运动迟缓。患者头颅MRI均可见不同程度脑萎缩，以额叶及中脑为著，部分患者出现“蜂鸟征”和“喇叭花征”改变。结论 PSP患者以运动迟缓为最常见首发症状，姿势不稳、易跌倒为常见的临床表现，垂直性眼肌麻痹最具诊断意义，头颅MRI检查有助于PSP诊断。
목적：탐토진행성핵상성마비（PSP）적림상화영상학특점。방법회고성분석12례림상진단적PSP환자적림상화영상학자료。결과12례환자주요증상위운동지완、자세불은、가성구마비화수직성안기마비，부분환자유인지공능장애、소편장애등。다수환자수발증상위운동지완。환자두로MRI균가견불동정도뇌위축，이액협급중뇌위저，부분환자출현“봉조정”화“나팔화정”개변。결론 PSP환자이운동지완위최상견수발증상，자세불은、역질도위상견적림상표현，수직성안기마비최구진단의의，두로MRI검사유조우PSP진단。
Objective To investigate the clinical and imaging features of progressive supranuclear paralysis (PSP). Methods 12 cases of PSP patients diagnosed clinical y were retrospectively analyzed based on clinical and imaging data. Re-sults The main symptoms of 12 PSP patients were bradykinesia, postural instability, pseudobulbar palsy and vertical ophthal-moplegia performance. Partial patients showed cognitive dysfunction and urinary disorders. The initial symptom of most patients was bradykinesia. Different levels of brain atrophy were observed in the cranial MRI of 12 patients, especial y in the frontal lobe and midbrain. The change of "hummingbird sign" and "morning glory sign"was observed in some of patients. Conclusion Bradykinesia was the most common initial symptom for PSP patients. Postural instability and easy to fal were the basic clinical manifestations. Vertical ophthalmoplegia indicated the greatest value of diagnosis Brain MRI assissed the PSP diagnosis.