中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
31期
111-111,113
,共2页
不规则抗体%输血安全%抗体筛查
不規則抗體%輸血安全%抗體篩查
불규칙항체%수혈안전%항체사사
Irregular antibody%Blood transfusion safety%Antibody screening
目的：探讨红细胞血型不规则抗体筛查在临床输血中的应用。方法：采用微柱凝胶法对19560例拟行输血治疗的患者进行不规则抗体检测和鉴定。结果：在19560例患者中，不规则抗体阳性108例，阳性率0.55%，其中男21例(0.27%)，女87例(0.74%)，不同性别阳性率比较差异有统计学意义(P＜0.05)；既往有妊娠或输血史阳性率显著高于无妊娠或输血史患者(P＜0.05)；不规则抗体阳性患者中，Rh血型系统47例，MNS血型系统5例，Lewis血型系统7例，冷抗体10例，自身抗体18例，药物抗体3例。结论：输血前对患者进行不规则抗体筛查和鉴定对确保输血安全及减少溶血性输血不良反应具有重要意义。
目的：探討紅細胞血型不規則抗體篩查在臨床輸血中的應用。方法：採用微柱凝膠法對19560例擬行輸血治療的患者進行不規則抗體檢測和鑒定。結果：在19560例患者中，不規則抗體暘性108例，暘性率0.55%，其中男21例(0.27%)，女87例(0.74%)，不同性彆暘性率比較差異有統計學意義(P＜0.05)；既往有妊娠或輸血史暘性率顯著高于無妊娠或輸血史患者(P＜0.05)；不規則抗體暘性患者中，Rh血型繫統47例，MNS血型繫統5例，Lewis血型繫統7例，冷抗體10例，自身抗體18例，藥物抗體3例。結論：輸血前對患者進行不規則抗體篩查和鑒定對確保輸血安全及減少溶血性輸血不良反應具有重要意義。
목적：탐토홍세포혈형불규칙항체사사재림상수혈중적응용。방법：채용미주응효법대19560례의행수혈치료적환자진행불규칙항체검측화감정。결과：재19560례환자중，불규칙항체양성108례，양성솔0.55%，기중남21례(0.27%)，녀87례(0.74%)，불동성별양성솔비교차이유통계학의의(P＜0.05)；기왕유임신혹수혈사양성솔현저고우무임신혹수혈사환자(P＜0.05)；불규칙항체양성환자중，Rh혈형계통47례，MNS혈형계통5례，Lewis혈형계통7례，랭항체10례，자신항체18례，약물항체3례。결론：수혈전대환자진행불규칙항체사사화감정대학보수혈안전급감소용혈성수혈불량반응구유중요의의。
Objective:To explore the application of RBC blood group irregular antibody screening in clinical blood transfusion. Methods:Using microcolum gel test given irregular antibody detection and identification for 19 560 patients with transfusion therapy.Results:In 19 560 patients,108 cases of irregular antibody was positive,and the positive rate was 0.55%,among which 21 cases(0.27%) were male and 87 cases(0.74%) were female;the difference between the positive rates of different genders was statistically significant(P<0.05).The positive rates of a history of pregnancy or blood transfusion were significantly higher than those of non pregnancy or blood transfusion patients(P<0.05).In the irregular antibody positive patients,47 cases were Rh blood group system;5 cases were MNS blood group system;7 cases were Lewis blood group system;10 cases were cold antibody;18 cases were autoantibody;3 cases were drug antibody.Conclusion:The irregular antibody screening and evaluation of patients before transfusion has great significance to ensure the blood transfusion safety and reduce hemolytic transfusion adverse reaction.
