中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
31期
106-107
,共2页
婴儿%新生%窒息%肌酸磷酸激酶同工酶%肌钙蛋白I%胆红素
嬰兒%新生%窒息%肌痠燐痠激酶同工酶%肌鈣蛋白I%膽紅素
영인%신생%질식%기산린산격매동공매%기개단백I%담홍소
Infant%Newly born%Asphyxia%Creatine phosphokinase isoenzyme%Cardiac troponin I%Bilirubin
目的：探讨血清肌酸磷酸激酶同工酶(CK-MB)、心肌肌钙蛋白I(CTnI)对窒息新生儿心肌损害的早期诊断价值。探讨胆红素(TBiL)的变化对窒息新生儿的临床意义。方法：窒息组60例(轻度组30例，重度组30例)患儿，对照组30例，新生儿出生后第1、4、11天测定其血清CKMB及CTnI，新生儿出生后24 h、第4天测定其TBiL。结果：新生儿出生后第1天窒息组CTnI明显高于对照组(P＜0.01)，重度窒息组明显高于轻度窒息组(P＜0.01)，之后下降。生后24 h，TBiL窒息组较对照组升高，重度窒息组明显高于轻度窒息组(P＜0.01)。新生儿出生后第4天，窒息组较对照组明显降低，病情越重降低越明显。结论：CTnI可用于窒息新生儿心肌损害的早期诊断，并可提示预后。胆红素作为抗氧化剂，可作为判断窒息病情轻重指标之一。
目的：探討血清肌痠燐痠激酶同工酶(CK-MB)、心肌肌鈣蛋白I(CTnI)對窒息新生兒心肌損害的早期診斷價值。探討膽紅素(TBiL)的變化對窒息新生兒的臨床意義。方法：窒息組60例(輕度組30例，重度組30例)患兒，對照組30例，新生兒齣生後第1、4、11天測定其血清CKMB及CTnI，新生兒齣生後24 h、第4天測定其TBiL。結果：新生兒齣生後第1天窒息組CTnI明顯高于對照組(P＜0.01)，重度窒息組明顯高于輕度窒息組(P＜0.01)，之後下降。生後24 h，TBiL窒息組較對照組升高，重度窒息組明顯高于輕度窒息組(P＜0.01)。新生兒齣生後第4天，窒息組較對照組明顯降低，病情越重降低越明顯。結論：CTnI可用于窒息新生兒心肌損害的早期診斷，併可提示預後。膽紅素作為抗氧化劑，可作為判斷窒息病情輕重指標之一。
목적：탐토혈청기산린산격매동공매(CK-MB)、심기기개단백I(CTnI)대질식신생인심기손해적조기진단개치。탐토담홍소(TBiL)적변화대질식신생인적림상의의。방법：질식조60례(경도조30례，중도조30례)환인，대조조30례，신생인출생후제1、4、11천측정기혈청CKMB급CTnI，신생인출생후24 h、제4천측정기TBiL。결과：신생인출생후제1천질식조CTnI명현고우대조조(P＜0.01)，중도질식조명현고우경도질식조(P＜0.01)，지후하강。생후24 h，TBiL질식조교대조조승고，중도질식조명현고우경도질식조(P＜0.01)。신생인출생후제4천，질식조교대조조명현강저，병정월중강저월명현。결론：CTnI가용우질식신생인심기손해적조기진단，병가제시예후。담홍소작위항양화제，가작위판단질식병정경중지표지일。
Objective:To explore the early diagnosis value of serum creatine phosphokinase isoenzyme(CK-MB) and cardiac troponin I(CTnI) in asphyxia newborn myocardial damage.To explore the clinical significance of the bilirubin(TBil) change in asphyxia newborn.Methods:60 children were the asphyxia group(the mild group in 30 cases,the severe group in 30 cases),and 30 cases were the control group.The serum CKMB and CTnI were measured at 1,4,11 days after birth.The TBiL was measured at 24 hours and 4 days after birth.Results:1 day after birth,CTnI of the asphyxia group was significantly higher than that of the control group(P<0.01),and the severe asphyxia group was significantly higher than the mild asphyxia group(P<0.01),then it decreased.24 hours after birth,TBiL of the asphyxia group was higher than that of the control group,and the severe asphyxia group was significantly higher than the mild asphyxia group.4 days after birth,the asphyxia group was significantly lower than the control group;the disease was more severe;the lower was more obvious.Conclusion:CTnI can be used for the early diagnosis of asphyxia newborn myocardial damage,and can prompt the prognosis.Bilirubin as an antioxidant can be used one index to judge the severity of asphyxia.
