CAJ | 학술논문

为了测定增乳健牛散（生乳散）的亚急性毒性反应，取昆明小鼠为试验动物，随机分组，以临床应用剂量的2、4、8倍饲喂给药，确定增乳健牛散（生乳散）在28d内对小鼠的亚急挫毒性反应。结果表明，各试验组小鼠全部健活，体征、体重、外观、行为、采食量及饲料利用率、脏器系数、血液生理生化指标、脏器结构均无异常。增乳健牛散（生乳散）对受试动物未见明显的亚急性毒性反应。
위료측정증유건우산（생유산）적아급성독성반응，취곤명소서위시험동물，수궤분조，이림상응용제량적2、4、8배사위급약，학정증유건우산（생유산）재28d내대소서적아급좌독성반응。결과표명，각시험조소서전부건활，체정、체중、외관、행위、채식량급사료이용솔、장기계수、혈액생리생화지표、장기결구균무이상。증유건우산（생유산）대수시동물미견명현적아급성독성반응。
Kunming mice were used to study the sub-acute toxicity of Chinese medicine powder Zengrujianniu San （ Shengru San） . The mice were grouped randomly and 2, 4 and 8 times doses were fed to them separately to study the sub-acute toxicity of Shengru San in 28 days. The results showed that all the mice lived well. The physical signs, body weight, appearance, behavior, food intake, feed efficiency, organ coefficient, the physiological and biochemical indexes of blood and organ structures all were normal. No obvious sub-acute toxicity was seen in tested animals.