CAJ | 학술논문

目的探讨他汀类降脂药物与静脉血栓栓塞症(VTE)发生的关系.方法选择3 000名健康体检者,他们只有血脂异常,不合并其他疾病.随机分为观察组和对照组,观察组给予他汀类降脂药物+饮食控制+运动疗法治疗,对照组给予饮食控制+运动疗法.1年后观察两组发生VTE的情况,进行统计学分析,其中合并其他疾病及死亡的被排除在外.结果两组的年龄、性别、入组前的血脂水平差异无统计学意义；对照组有7名发生VTE,而观察组有2名发生VTE,两组发生率差异有统计学意义(P＜0.05).结论他汀类降脂药物有降低VTE发生的作用.
목적 탐토타정류강지약물여정맥혈전전새증(VTE)발생적관계.방법 선택3 000명건강체검자,타문지유혈지이상,불합병기타질병.수궤분위관찰조화대조조,관찰조급여타정류강지약물+음식공제+운동요법치료,대조조급여음식공제+운동요법.1년후관찰량조발생VTE적정황,진행통계학분석,기중합병기타질병급사망적피배제재외.결과 량조적년령、성별、입조전적혈지수평차이무통계학의의；대조조유7명발생VTE,이관찰조유2명발생VTE,량조발생솔차이유통계학의의(P＜0.05).결론 타정류강지약물유강저VTE발생적작용.
Objective To study the relationship between statins and venous thromboembolism (VTE).Methods 3 000 individuals with dyslipidemia were selected,and they had no other diseases.The individuals were randomly divided into two groups:observation group was given statins,controling food,and moving,control group was given controling food and moving therapy.After one year,the number of cases of VTE in the two groups was observed and compared with statistical analysis.Results There was no statistical significanse in age,sex,and blood lipid level between the two groups.Seven individuals occurred VTE in control group and two individuals occurred VTE in observation group.There was statistical significance in incidence rate of VTE between the two groups (P ＜0.05).Conclusions Statins can decrease the occurrence of VTE.