CAJ | 학술논문

目的：研究炎性反应标志物超敏C反应蛋白（high-sensitivity C-reactive protein，hs-CRP）与2型糖尿病(type 2 diabetes mel itus, DM2)伴随或者不伴随高血压是否存在相关性。方法入组13例2型糖尿病患者无合并症，17例高血压患者(high blood pressure, HBP)，34例2型糖尿病伴随高血压患者（DM2+HBP），25例健康体检对照组，电化学免疫发光法测定血清hs-CRP。结果健康对照组hs-CRP水平明显低于HBP+DM2患者（p＜0.05），DM2伴随HBP与hs-CRP水平显著相关（n=89， r=0.25， p=0.0160）。讨论 DM2+HBP患者具有相对活跃的炎性状态。
목적：연구염성반응표지물초민C반응단백（high-sensitivity C-reactive protein，hs-CRP）여2형당뇨병(type 2 diabetes mel itus, DM2)반수혹자불반수고혈압시부존재상관성。방법입조13례2형당뇨병환자무합병증，17례고혈압환자(high blood pressure, HBP)，34례2형당뇨병반수고혈압환자（DM2+HBP），25례건강체검대조조，전화학면역발광법측정혈청hs-CRP。결과건강대조조hs-CRP수평명현저우HBP+DM2환자（p＜0.05），DM2반수HBP여hs-CRP수평현저상관（n=89， r=0.25， p=0.0160）。토론 DM2+HBP환자구유상대활약적염성상태。
Objective We study if plasma levels of hs-CRP related to DM2+HBP patients. Methods hs-CRP were measured in subjects with DM2 and /or HBP, including 13 patients with DM2, 17 patients with HBP, 34 patients with DM2+HBP, and 25 healthy test control subjects. hs-CRP tested by Electro-Chemiluminescence Immuno Assay (ECLI). Results The plasma hs-CRP levels were significantly lower in the controls than in the DM2+HBP group (p<0.05), DM2 associated with HBP was also correlated with increased plasma hs-CRP levels (n=89, r =0.25, p=0.0160). Conclusions This study suggests that patients with two associated diseases have a more active inflammatory state.