现代农业科技
現代農業科技
현대농업과기
XIANDAIHUA NONGYE
2012年
12期
113-114
,共2页
纳米铜%C—N偶联%农药中间体
納米銅%C—N偶聯%農藥中間體
납미동%C—N우련%농약중간체
nano copper%C-N coupling%pesticide intermediates
铜催化芳基卤代物与含氮化合物的偶联反应在当代有机合成中是极其重要的构建C—N键的方法。该研究通过溶剂热法制备片状、开口球及闭口球的纳米铜。对纳米铜催化C—N偶联反应体系进行优化改进，最佳反应条件为5t001％催化剂、以氢氧化钾为碱、在二甲亚砜中反应24h．最后在室温无配体条件下拓展了纳米铜催化C—N偶联反应的应用范围。
銅催化芳基滷代物與含氮化閤物的偶聯反應在噹代有機閤成中是極其重要的構建C—N鍵的方法。該研究通過溶劑熱法製備片狀、開口毬及閉口毬的納米銅。對納米銅催化C—N偶聯反應體繫進行優化改進，最佳反應條件為5t001％催化劑、以氫氧化鉀為堿、在二甲亞砜中反應24h．最後在室溫無配體條件下拓展瞭納米銅催化C—N偶聯反應的應用範圍。
동최화방기서대물여함담화합물적우련반응재당대유궤합성중시겁기중요적구건C—N건적방법。해연구통과용제열법제비편상、개구구급폐구구적납미동。대납미동최화C—N우련반응체계진행우화개진，최가반응조건위5t001％최화제、이경양화갑위감、재이갑아풍중반응24h．최후재실온무배체조건하탁전료납미동최화C—N우련반응적응용범위。
The Cu-catalyzed cross-coupling of aryl halides and N-H containing compounds has rapidly emerged as an indispensable method for the construction of C-N bonds in contemporary organic synthesis.The research made various nano copper with different appearance,including sheet, open ball and closed ball.Nano-copper catalyzed C-N coupling reaction system were improved, the optimum reaction conditions were as follows： 5 mol% catalyst ,potassium hydroxide ,alkali, reaction in dimethyl sulfoxide for ：24 hours, and finally expanded its range of applications under room temperature.
