CAJ | 학술논문

目的探讨非甾体抗炎药(NSAIDs)致中青年患者上消化道出血的临床特点.方法回顾分析81例非甾体抗炎药中青年患者的临床资料.结果本组81患者2周内均有服用NSAIDs病史,都经大便潜血及纤维胃镜确诊.伴有腹部疼痛症状18例占22.2％(18/81)；有嗜咖啡或酸辣饮食习惯53例(占65.4％)；有吸烟史48例(占59.3％).结论中青年人群服用NSAIDs引起的上消化道出血起病隐匿、临床症状轻和体征不明显的特点,应引起临床医师和药师的警惕.
목적 탐토비치체항염약(NSAIDs)치중청년환자상소화도출혈적림상특점.방법 회고분석81례비치체항염약중청년환자적림상자료.결과 본조81환자2주내균유복용NSAIDs병사,도경대편잠혈급섬유위경학진.반유복부동통증상18례점22.2％(18/81)；유기가배혹산랄음식습관53례(점65.4％)；유흡연사48례(점59.3％).결론 중청년인군복용NSAIDs인기적상소화도출혈기병은닉、림상증상경화체정불명현적특점,응인기림상의사화약사적경척.
Objective To explore the clinical features of upper gastrointestinal hemorrhage caused by non-steroidal anti-inflammatory drugs(NSAIDs)in young and middle-aged patients.Methods The clinical data of 81 young and middle-aged patients with upper gastrointestinal hemorrhage caused by NSAIDs were retrospectively analyzed.Results All patients,taking NSAIDs within two weeks,diagnosed by fecal occult blood and fiber gastroscope.18 cases(22.2％)complicated with abdominal pain.53 cases (65.4％)addicted to coffee or sour-spicy food.48 cases(59.3％)smoked.Conclusions Upper gastrointestinal hemorrhage caused by NSAIDs in young and middle-aged people is occult onset and has mild clinical symptoms and unobvious signs.Clinicians and pharmacists should pay attention to it.