中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
31期
18-19
,共2页
低分子肝素钠%硝酸甘油%冠心病
低分子肝素鈉%硝痠甘油%冠心病
저분자간소납%초산감유%관심병
Low molecular weight heparin sodium%Nitroglycerin%Coronary heart disease
目的：探讨冠心病患者应用低分子肝素钠与硝酸甘油联合治疗的临床效果。方法：2012年5月-2013年5月收治冠心病患者85例，经冠状动脉造影证实为冠心病，作为研究对象，随机将患者分为观察组43例以及对照组42例，对照组给予硝酸甘油治疗，观察组在对照组的基础上给予低分子肝素钠治疗，对比分析两组患者治疗前后心绞痛发作次数、心绞痛缓解时间、心电图ST段下移情况以及血液动力学指标改善情况。结果：两组患者治疗后心绞痛发作次数、心绞痛持续时间、心电图ST段下移情况优于治疗前，而观察组治疗后心绞痛发作次数、心绞痛持续时间、心电图ST段下移情况均优于对照组，差异有统计学意义(P＜0.05)。治疗后观察组血浆黏度、血沉、纤维蛋白原、红细胞电泳时间、红细胞聚集性、血小板聚集功能等血液动力学指标显著高于对照组，差异具有统计学意义(P＜0.05)。结论：低分子肝素钠联合硝酸甘油治疗冠心病能有效提高患者治疗效果，改善患者血液动力学指标，有利于患者预后。
目的：探討冠心病患者應用低分子肝素鈉與硝痠甘油聯閤治療的臨床效果。方法：2012年5月-2013年5月收治冠心病患者85例，經冠狀動脈造影證實為冠心病，作為研究對象，隨機將患者分為觀察組43例以及對照組42例，對照組給予硝痠甘油治療，觀察組在對照組的基礎上給予低分子肝素鈉治療，對比分析兩組患者治療前後心絞痛髮作次數、心絞痛緩解時間、心電圖ST段下移情況以及血液動力學指標改善情況。結果：兩組患者治療後心絞痛髮作次數、心絞痛持續時間、心電圖ST段下移情況優于治療前，而觀察組治療後心絞痛髮作次數、心絞痛持續時間、心電圖ST段下移情況均優于對照組，差異有統計學意義(P＜0.05)。治療後觀察組血漿黏度、血沉、纖維蛋白原、紅細胞電泳時間、紅細胞聚集性、血小闆聚集功能等血液動力學指標顯著高于對照組，差異具有統計學意義(P＜0.05)。結論：低分子肝素鈉聯閤硝痠甘油治療冠心病能有效提高患者治療效果，改善患者血液動力學指標，有利于患者預後。
목적：탐토관심병환자응용저분자간소납여초산감유연합치료적림상효과。방법：2012년5월-2013년5월수치관심병환자85례，경관상동맥조영증실위관심병，작위연구대상，수궤장환자분위관찰조43례이급대조조42례，대조조급여초산감유치료，관찰조재대조조적기출상급여저분자간소납치료，대비분석량조환자치료전후심교통발작차수、심교통완해시간、심전도ST단하이정황이급혈액동역학지표개선정황。결과：량조환자치료후심교통발작차수、심교통지속시간、심전도ST단하이정황우우치료전，이관찰조치료후심교통발작차수、심교통지속시간、심전도ST단하이정황균우우대조조，차이유통계학의의(P＜0.05)。치료후관찰조혈장점도、혈침、섬유단백원、홍세포전영시간、홍세포취집성、혈소판취집공능등혈액동역학지표현저고우대조조，차이구유통계학의의(P＜0.05)。결론：저분자간소납연합초산감유치료관심병능유효제고환자치료효과，개선환자혈액동역학지표，유리우환자예후。
Objective:To explore the clinical effect of using low molecular weight heparin sodium combined with nitroglycerin in the treatment of patients with coronary heart disease.Methods:85 patients with coronary heart disease were selected from May 2012 to May 2013.They were confirmed for coronary heart disease by coronary arteriongraphy as the research objects.The patients were randomly divided into the observation group in 43 cases and the control group in 42 cases.The control group were given nitroglycerin treatment.The observation group were given low molecular weight heparin sodium treatment on the basis of in the control group.The angina attack frequency,angina relief time,electrocardiogram ST down condition and hemodynamic index improvement condition before and after treatment of two groups were contrastively analyzed.Results:The angina attack frequency, angina relief time and electrocardiogram ST down condition after treatment of two groups were better than these before treatment, and the angina attack frequency,angina relief time and electrocardiogram ST down condition after treatment of the observation group were better than those of the control group.The difference was statistically significant(P<0.05).The plasma viscosity,blood sedimentation,fibrinogen,erythrocyte electrophoresis time,erythrocyte aggregation,platelet aggregation function and other hemodynamic indexes after treatment of the observation group were significantly higher than those of the control group.The difference was statistically significant(P<0.05).Conclusion:The low molecular weight heparin sodium combined with nitroglycerin in the treatment of coronary heart disease can improve the treatment effect of patients,improve the hemodynamic indexes of patients,and help the patients prognosis.
