中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
CHINESE JOURNAL OF OSTEOPOROSIS
2013年
12期
1281-1285
,共5页
戴蓉%刘华清%顾勤明%张增利
戴蓉%劉華清%顧勤明%張增利
대용%류화청%고근명%장증리
老年性骨折%2型糖尿病%血管性痴呆%病例对照研究
老年性骨摺%2型糖尿病%血管性癡呆%病例對照研究
노년성골절%2형당뇨병%혈관성치태%병례대조연구
Senile fracture%Type 2 diabetes mellitus%Vascular dementia%Case-control study
目的：采用病例对照法初步分析2型糖尿病与老年性骨折的关系。方法根据纳入和排除标准筛选大于60周岁的住院糖尿病和非糖尿病病人，收集其人口学特征、病史和治疗情况，采用SAS 9.2软件建立logistic多元回归模型分析调整多种因素后2型糖尿病与老年性骨折的关系。结果共纳入150例病例，平均年龄82.39岁。女性（ OR：3.314，95％CI 1.191～9.218）和年龄（每增加5岁OR：1.399，95％CI 1.010～1.939）是老年性骨折的危险因素；调整年龄和性别等混杂因素的影响之后，患2型糖尿病和血管性痴呆的患者发生老年性骨折的风险更低，OR值分别为0.237（95％CI 0.072～0.787）和0.091（95％CI 0.015～0.742）。结论本研究提示在高龄住院老年人中2型糖尿病与老年性骨折呈负相关，其原因有待更大样本量的研究进行分析。
目的：採用病例對照法初步分析2型糖尿病與老年性骨摺的關繫。方法根據納入和排除標準篩選大于60週歲的住院糖尿病和非糖尿病病人，收集其人口學特徵、病史和治療情況，採用SAS 9.2軟件建立logistic多元迴歸模型分析調整多種因素後2型糖尿病與老年性骨摺的關繫。結果共納入150例病例，平均年齡82.39歲。女性（ OR：3.314，95％CI 1.191～9.218）和年齡（每增加5歲OR：1.399，95％CI 1.010～1.939）是老年性骨摺的危險因素；調整年齡和性彆等混雜因素的影響之後，患2型糖尿病和血管性癡呆的患者髮生老年性骨摺的風險更低，OR值分彆為0.237（95％CI 0.072～0.787）和0.091（95％CI 0.015～0.742）。結論本研究提示在高齡住院老年人中2型糖尿病與老年性骨摺呈負相關，其原因有待更大樣本量的研究進行分析。
목적：채용병례대조법초보분석2형당뇨병여노년성골절적관계。방법근거납입화배제표준사선대우60주세적주원당뇨병화비당뇨병병인，수집기인구학특정、병사화치료정황，채용SAS 9.2연건건립logistic다원회귀모형분석조정다충인소후2형당뇨병여노년성골절적관계。결과공납입150례병례，평균년령82.39세。녀성（ OR：3.314，95％CI 1.191～9.218）화년령（매증가5세OR：1.399，95％CI 1.010～1.939）시노년성골절적위험인소；조정년령화성별등혼잡인소적영향지후，환2형당뇨병화혈관성치태적환자발생노년성골절적풍험경저，OR치분별위0.237（95％CI 0.072～0.787）화0.091（95％CI 0.015～0.742）。결론본연구제시재고령주원노년인중2형당뇨병여노년성골절정부상관，기원인유대경대양본량적연구진행분석。
Objective To analyze the correlation between type 2 diabetes mellitus and senile fractures preliminarily in a case-control study.Methods According to the inclusion criteria and exclusion criteria, hospitalized patients elder than 60 years old, with or without diabetes, were screened.The demographic characteristics, medical history, and treatment conditions of all the patients were recorded.After adjusting for confounding factors, logistic multivariate regression was performed to analyze the correlation between type 2 diabetes mellitus and senile fractures using a SAS 9.2 software.Results A total of 150 patients, with an average age of 82.39 years old, were included in this study.Female (OR:3.314, 95%CI 1.191-9.218) and age (per 5 years increase, OR:1.399, 95%CI 1.010-1.939) were risk factors of senile fractures.After adjusting for confounding factors such as age and gender, the risk of senile fractures in patients with type 2 diabetes mellitus or vascular dementia was lower, and the OR was 0.237 (95%CI 0.072-0.787) and 0.091 (95% CI 0.015-0.742), respectively.Conclusion The results of this study reveal that there is negative correlation between type 2 diabetes mellitus and senile fractures in hospitalized patients with advanced age.And further research with larger sample size needs to be performed to analyze the reason.
