中国医疗前沿
中國醫療前沿
중국의료전연
CHINA HEALTHCARE INNOVATION
2013年
21期
28-28,29
,共2页
老年慢性阻塞性肺疾病%糖尿病%临床特点%治疗转归
老年慢性阻塞性肺疾病%糖尿病%臨床特點%治療轉歸
노년만성조새성폐질병%당뇨병%림상특점%치료전귀
Elderly patients with chronic obstructive pulmonary disease%Diabetes%Clinical feature%Treatment outcomes
目的：分析老年慢性阻塞性肺疾病(COPD)合并糖尿病(DM)患者的临床特点及治疗转归。方法将96例老年COPD患者分为单纯COPD组及合并DM组，分析两组临床症状、实验室检查及治疗及转归。结果观察组下肢浮肿及静脉血栓的发生率高于对照组，(P <0.05)，D-二聚体、WBC及痰液培养阳性率高于对照组(P <0.05)，PaO2、U-ALB低于对照组(P <0.05)， PaCO2高于对照组(P >0.05)；观察组抗生素使用情况、平均住院时间多于对照组(P <0.05)；两组治疗有效率及死亡率无统计学差异(P >0.05)。结论老年急性加重期COPD合并DM可明显增加患者细菌感染的发生几率，增加血气分析指标的异常，加重呼吸衰竭的发生概率；导致患者不同程度营养不良的发生，增加抗生素使用时间，延长住院治疗时间，严重影响患者的预后，必须予以高度重视。
目的：分析老年慢性阻塞性肺疾病(COPD)閤併糖尿病(DM)患者的臨床特點及治療轉歸。方法將96例老年COPD患者分為單純COPD組及閤併DM組，分析兩組臨床癥狀、實驗室檢查及治療及轉歸。結果觀察組下肢浮腫及靜脈血栓的髮生率高于對照組，(P <0.05)，D-二聚體、WBC及痰液培養暘性率高于對照組(P <0.05)，PaO2、U-ALB低于對照組(P <0.05)， PaCO2高于對照組(P >0.05)；觀察組抗生素使用情況、平均住院時間多于對照組(P <0.05)；兩組治療有效率及死亡率無統計學差異(P >0.05)。結論老年急性加重期COPD閤併DM可明顯增加患者細菌感染的髮生幾率，增加血氣分析指標的異常，加重呼吸衰竭的髮生概率；導緻患者不同程度營養不良的髮生，增加抗生素使用時間，延長住院治療時間，嚴重影響患者的預後，必鬚予以高度重視。
목적：분석노년만성조새성폐질병(COPD)합병당뇨병(DM)환자적림상특점급치료전귀。방법장96례노년COPD환자분위단순COPD조급합병DM조，분석량조림상증상、실험실검사급치료급전귀。결과관찰조하지부종급정맥혈전적발생솔고우대조조，(P <0.05)，D-이취체、WBC급담액배양양성솔고우대조조(P <0.05)，PaO2、U-ALB저우대조조(P <0.05)， PaCO2고우대조조(P >0.05)；관찰조항생소사용정황、평균주원시간다우대조조(P <0.05)；량조치료유효솔급사망솔무통계학차이(P >0.05)。결론노년급성가중기COPD합병DM가명현증가환자세균감염적발생궤솔，증가혈기분석지표적이상，가중호흡쇠갈적발생개솔；도치환자불동정도영양불량적발생，증가항생소사용시간，연장주원치료시간，엄중영향환자적예후，필수여이고도중시。
Objective To analyze the characteristics of elderly patients with chronic obstructive pulmonary and diabetes mellitus. Methods 96 cases of elderly patients with COPD were divided into the simple group(the control group) and the combined DM group(the study group). The clinical symptoms, laboratory tests and treatment and prognosis of the two groups were analyzed. Results The lower extremity edema and venous thrombosis rate of the the study group was higher than that of the control group(P <0.05). The D-dimer, WBC and sputum culture positive rate of the the study group was higher than that of the control group(P <0.05). The PaO2 and U-ALB of the the study group was lower than those of the control group(P <0.05). While the PaCO2 of the study group was higher than that of the control group(P >0.05). The antibiotics use time and average length of stay of the study group was higher than those of the control group(P <0.05). The efficiency of treatment and mortality in the two groups showed no statistically significant(P >0.05). Conclusion Elderly patients with acute exacerbation of COPD and DM could significantly increase the occurrence of bacterial infection and abnormal in blood gas analysis, increase the probability of occurrence of respiratory failure, cause varying degrees of malnutrition in patients and the antibiotic use time, prolonge the hospitalization time, which was with seriously affect for the patient's prognosis and must be highly valued.
