CAJ | 학술논문

目的探讨功能社区脂肪肝患病率及其相关因素，为脂肪肝在功能社区早期的健康管理干预提供依据。方法选取2012年7月我院在某公司体检的具有完整资料的健康体检者2386例，分为脂肪肝组和非脂肪肝组，通过性别、年龄分层后比较脂肪肝的患病率，并将脂肪肝患者的体重指数、血压、血脂、空腹血糖、血尿酸与非脂肪肝组进行对比分析，对脂肪肝的相关危险因素进行了Logistic多因素回归分析。结果（1）共检出脂肪肝356例，总患病率为14.9％，男性患病率显著高于女性（ P＜0.01）；脂肪肝患病率随年龄的增加而增加，40～49岁最高达25.2％。（2）各年龄组脂肪肝的检出率均随着体型的变化（正常、超重、肥胖）依次增加（P＜0.01）。正常体重组和超重组比较各年龄组脂肪肝检出率差异有统计学意义（P ＜0．01）；肥胖组各年龄组脂肪肝检出率差异无统计学意义（P＞0.05）。（3）脂肪肝组的代谢综合征的检出率明显高于非脂肪肝组（35.8％vs．6.8％，P＜0.001），脂肪肝组超重、肥胖、血压、空腹血糖、甘油三酯等增高的检出率明显高于非脂肪肝组（P均＜0.01）。（4）多因素Logistic回归分析提示，脂肪肝危险因素包括年龄、空腹血糖、甘油三酯、舒张压、血尿酸、超重和肥胖， OR值分别为1.299、1.286、1.795、1.376、1.374、5.771、27.206。结论超重、肥胖、高血糖、高血压、血脂、血尿酸异常是该人群脂肪肝发病的主要危险因素，为早期干预脂肪肝的健康管理方案提供重要依据。
목적탐토공능사구지방간환병솔급기상관인소，위지방간재공능사구조기적건강관리간예제공의거。방법선취2012년7월아원재모공사체검적구유완정자료적건강체검자2386례，분위지방간조화비지방간조，통과성별、년령분층후비교지방간적환병솔，병장지방간환자적체중지수、혈압、혈지、공복혈당、혈뇨산여비지방간조진행대비분석，대지방간적상관위험인소진행료Logistic다인소회귀분석。결과（1）공검출지방간356례，총환병솔위14.9％，남성환병솔현저고우녀성（ P＜0.01）；지방간환병솔수년령적증가이증가，40～49세최고체25.2％。（2）각년령조지방간적검출솔균수착체형적변화（정상、초중、비반）의차증가（P＜0.01）。정상체중조화초중조비교각년령조지방간검출솔차이유통계학의의（P ＜0．01）；비반조각년령조지방간검출솔차이무통계학의의（P＞0.05）。（3）지방간조적대사종합정적검출솔명현고우비지방간조（35.8％vs．6.8％，P＜0.001），지방간조초중、비반、혈압、공복혈당、감유삼지등증고적검출솔명현고우비지방간조（P균＜0.01）。（4）다인소Logistic회귀분석제시，지방간위험인소포괄년령、공복혈당、감유삼지、서장압、혈뇨산、초중화비반， OR치분별위1.299、1.286、1.795、1.376、1.374、5.771、27.206。결론초중、비반、고혈당、고혈압、혈지、혈뇨산이상시해인군지방간발병적주요위험인소，위조기간예지방간적건강관리방안제공중요의거。
Objective To explore the prevalence rate of fatty liver and the relationship between it and it′s related factors in order to provide evidence for its early intervention .Methods A total of 2386 cases were included in this study which was carried out using our hospital Mobile Physical Examination Vehicle in July 2012,with complete information developed.The physical examination results were analyzed with statistical method .Results (1)There were 356 persons diagnosed of fatty liver disease by B-type ultrasonic scanning in this study .The total prevalence rate of fatty liver was 14.9%.Men had a higher prevalence than women ( 16.1% vs.4.5%, P <0.01 ) .The trend of prevalence of fatty liver was growing with the age increasing (P<0.01).(2)For each age group,the prevalence rate of fatty liver increased with level growth of BMI (normal,overweight,obesity,P<0.01).The difference of prevalence rate among all age sub-groups proved statistically significant ( P<0.01 ) for both normal weight group and overweight group,while P>0.05 for obesity group.(3)Prevalence of metabolic syndrome was higher in fatty liver group than in non fatty liver group(P<0.01).(4)Multiple regression analysis showed that age,FBG,TG,DBP,UA,overweight and obesity were risk factors for fatty liver (OR:1.299,1.286,1.795,1.376,1.374,5.771,27.206,respectively). Conclusion High blood pressure,overweight,obesity,dyslipidemia and increasing of UA are closely correlated with fatty liver disease .This is to provide an important evidence for early health management program of fatty liver .