中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2013年
7期
1267-1268
,共2页
酵母样真菌%耐药性%白色念珠菌%真菌分布
酵母樣真菌%耐藥性%白色唸珠菌%真菌分佈
효모양진균%내약성%백색념주균%진균분포
Yeast-like fungus%Resistant%Candida albicans%The fungus distribution
目的：阶段性总结和分析真菌分布情况及耐药性，以提高临床的治疗与预防效果，为我国医疗感染用药以及疾病治疗预防提供指导意见。方法：取我院患者送检的分泌物、尿液、粪便、咽拭子等的化验结果及药敏报告，经真菌培养鉴定，共检出酵母样真菌150例，药敏试验检测真菌的耐药性。结果：酵母样真菌分布按百分率由高到底排序为：白色念珠菌(65.33%)、光滑念珠菌(14.67%)、热带念珠菌(12%)、克柔念珠菌(5.33%)和近平滑念珠菌(2.67%)。按敏感率排序：两性霉素B(92%)、伏立康唑(75.33%)、氟胞嘧啶(64.67%)、益康唑(58%)、氟康唑(58%)、酮康唑(57.33%)、咪康唑(41.33%)、伊曲康唑(18%)；按耐药率排序：两性霉素B(5.33%)、伏立康唑(7.33%)、氟康唑(15.33%)、氟胞嘧啶(29.33%)、咪康唑(32%)、益康唑(32.67%)、酮康唑(33.33%)、伊曲康唑(74.67%)。结论：白色念珠菌是酵母样真菌感染的主要菌种，两性霉素B可作为临床用药的首选，伏立康唑次之，抗菌素用药还应谨慎，勿滥用。
目的：階段性總結和分析真菌分佈情況及耐藥性，以提高臨床的治療與預防效果，為我國醫療感染用藥以及疾病治療預防提供指導意見。方法：取我院患者送檢的分泌物、尿液、糞便、嚥拭子等的化驗結果及藥敏報告，經真菌培養鑒定，共檢齣酵母樣真菌150例，藥敏試驗檢測真菌的耐藥性。結果：酵母樣真菌分佈按百分率由高到底排序為：白色唸珠菌(65.33%)、光滑唸珠菌(14.67%)、熱帶唸珠菌(12%)、剋柔唸珠菌(5.33%)和近平滑唸珠菌(2.67%)。按敏感率排序：兩性黴素B(92%)、伏立康唑(75.33%)、氟胞嘧啶(64.67%)、益康唑(58%)、氟康唑(58%)、酮康唑(57.33%)、咪康唑(41.33%)、伊麯康唑(18%)；按耐藥率排序：兩性黴素B(5.33%)、伏立康唑(7.33%)、氟康唑(15.33%)、氟胞嘧啶(29.33%)、咪康唑(32%)、益康唑(32.67%)、酮康唑(33.33%)、伊麯康唑(74.67%)。結論：白色唸珠菌是酵母樣真菌感染的主要菌種，兩性黴素B可作為臨床用藥的首選，伏立康唑次之，抗菌素用藥還應謹慎，勿濫用。
목적：계단성총결화분석진균분포정황급내약성，이제고림상적치료여예방효과，위아국의료감염용약이급질병치료예방제공지도의견。방법：취아원환자송검적분비물、뇨액、분편、인식자등적화험결과급약민보고，경진균배양감정，공검출효모양진균150례，약민시험검측진균적내약성。결과：효모양진균분포안백분솔유고도저배서위：백색념주균(65.33%)、광활념주균(14.67%)、열대념주균(12%)、극유념주균(5.33%)화근평활념주균(2.67%)。안민감솔배서：량성매소B(92%)、복립강서(75.33%)、불포밀정(64.67%)、익강서(58%)、불강서(58%)、동강서(57.33%)、미강서(41.33%)、이곡강서(18%)；안내약솔배서：량성매소B(5.33%)、복립강서(7.33%)、불강서(15.33%)、불포밀정(29.33%)、미강서(32%)、익강서(32.67%)、동강서(33.33%)、이곡강서(74.67%)。결론：백색념주균시효모양진균감염적주요균충，량성매소B가작위림상용약적수선，복립강서차지，항균소용약환응근신，물람용。
Objective:Phase summary and analysis of fungal distribution and drug resistance,to improve the treatment and prevention of clinical effect,and to provide guidance for our medical infection medication,and treatment of disease prevention.Methods:Secretions,ur ine,feces,throat swab test results and susceptibility reports of censorship in patients in our hospital.Fungal culture identified 150 cases were detected in the yeast-like fungi,susceptibility test for detection of fungal resistance.Results:Yeast-like fungi distribution by percentage high in the end sort:Candida glabrata,Candida albicans (65.33%)、Smooth candida(14.67%),Candida tropicalis(12%),krusei candidiasis (5.33%) and Candida parapsilosis(2.67%).Sort by sensitive rate:amphotericin B (92%),voriconazole (75.33%) of flucytosine (64.67%),econazole (58%),fluconazole (58%),ketoconazole (57.33%),the miconazole (41.33%),Iraq Qu itraconazole (18%);Sort by resistance rates:Amphotericin B (5.33%),voriconazole (7.33%),fluconazole (15.33%) of flucytosine (29.33%),miconazole (32%),econazole (32.67%),ketoconazole (33.33%),the Iraqi song itraconazole (74.67%).Conclusion:Candida albicans is the main strains of yeast-like fungal infections,amphotericin B as the first choice of clinical medicine,voriconazole followed,antibiotic medication should also be noted that caution, do not abuse.
