中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2013年
7期
1238-1239
,共2页
尿毒清颗粒%慢性肾功能衰竭%依那普利%临床疗效
尿毒清顆粒%慢性腎功能衰竭%依那普利%臨床療效
뇨독청과립%만성신공능쇠갈%의나보리%림상료효
Urinary poisonous clear particles%Chronic Renal failure%Enalaprilat%Clinical curative effect
目的：研究尿毒清颗粒与依那普利相配合对慢性肾功能衰竭(CRF)延缓的临床疗效。方法：86例CRF住院患者随机分成两组,即治疗组44例,对照组42例,对照组患者给予依那普利与低蛋白饮食,其含量分别为6mg,qd与0.5g/(kg·d),而治疗组是在对照组的治疗方法前提下,又加用了尿毒清颗粒,其使用量为每天3次,每次5g,两组疗程都是两年,对两组患者临床治疗前后的尿量、血压、尿素氮、血生化、血肌酐与24h的尿蛋白定量变化进行研究。结果：两组患者临床治疗之后,其血肌酐与尿素氮均显著降低,P<0.01或者P<0.05,并且治疗组比对照组的下降幅度更为显著P<0.01,对照组有效率为76.19%,治疗组有效率为93.18%,治疗组有效率比对照组要明显高,其差异性显著P<0.05。结论：尿毒清颗粒与依那普利相配合,对CRF延缓,临床疗效满意且安全性好。
目的：研究尿毒清顆粒與依那普利相配閤對慢性腎功能衰竭(CRF)延緩的臨床療效。方法：86例CRF住院患者隨機分成兩組,即治療組44例,對照組42例,對照組患者給予依那普利與低蛋白飲食,其含量分彆為6mg,qd與0.5g/(kg·d),而治療組是在對照組的治療方法前提下,又加用瞭尿毒清顆粒,其使用量為每天3次,每次5g,兩組療程都是兩年,對兩組患者臨床治療前後的尿量、血壓、尿素氮、血生化、血肌酐與24h的尿蛋白定量變化進行研究。結果：兩組患者臨床治療之後,其血肌酐與尿素氮均顯著降低,P<0.01或者P<0.05,併且治療組比對照組的下降幅度更為顯著P<0.01,對照組有效率為76.19%,治療組有效率為93.18%,治療組有效率比對照組要明顯高,其差異性顯著P<0.05。結論：尿毒清顆粒與依那普利相配閤,對CRF延緩,臨床療效滿意且安全性好。
목적：연구뇨독청과립여의나보리상배합대만성신공능쇠갈(CRF)연완적림상료효。방법：86례CRF주원환자수궤분성량조,즉치료조44례,대조조42례,대조조환자급여의나보리여저단백음식,기함량분별위6mg,qd여0.5g/(kg·d),이치료조시재대조조적치료방법전제하,우가용료뇨독청과립,기사용량위매천3차,매차5g,량조료정도시량년,대량조환자림상치료전후적뇨량、혈압、뇨소담、혈생화、혈기항여24h적뇨단백정량변화진행연구。결과：량조환자림상치료지후,기혈기항여뇨소담균현저강저,P<0.01혹자P<0.05,병차치료조비대조조적하강폭도경위현저P<0.01,대조조유효솔위76.19%,치료조유효솔위93.18%,치료조유효솔비대조조요명현고,기차이성현저P<0.05。결론：뇨독청과립여의나보리상배합,대CRF연완,림상료효만의차안전성호。
Objective:To study the urine poisonous clear particles and enalaprilat phase fit for chronic renal failure delay clinical curative effect. Methods: 86 cases of chronic renal failure hospitalized patients were randomly divided into two groups, namely the treatment group 44 cases and control 42 cases, control group patients give enalaprilat and low protein diet, the content of 6 mg respectively, qd and 0.5 g/kg · d), and the treatment group is in the control group therapy premise, with the added urine poisonous clear grain, its usage every day for three times, each time 5 g, two groups of treatment are two years, the two groups of patients before and after the clinical treatment of urine, blood pressure, urea nitrogen, serum creatinine and blood biochemistry, 24 h urine protein quantitative change research. Results:Two groups of patients after clinical treatment, the serum creatinine and urea nitrogen were significantly lower, P<0.01 or P<0.05, and the treatment group than in the control group decline was more significant (P<0.01), and the control group, the effective rate was 76.19%in the treatment group, the effective rate was 93.18%in the treatment group than the control group significantly high efficient, the significant differences P<0.05. Conclusion:Urinary poisonous clear particles and enalaprilat suitably, for chronic renal function failure delay, clinical curative effect satisfaction and good safety.
