中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2013年
7期
1230-1230,1232
,共2页
慢性乙型肝炎%阿德福韦酯%拉米夫定%疗效
慢性乙型肝炎%阿德福韋酯%拉米伕定%療效
만성을형간염%아덕복위지%랍미부정%료효
Chronic hepatitis%Adefovir%Lamivudine%Effective
目的：观察阿德福韦酯联用拉米夫定治疗慢性乙型肝炎(CHB)的疗效。方法：选择68例CHB患者分为A、B两组,A组38例采用阿德福韦酯联合拉米夫定治疗1年；B组单用阿德福韦酯治疗1年,拉米夫定100 mg,阿德福韦酯10 mg,均1次/d。结果：在治疗初期单用ADV或与LAM联用,均抑制病毒均有效,若长期服用,两药联用效果更好。结论：拉米夫定联合阿德福韦酯是CHB较好的治疗方案。
目的：觀察阿德福韋酯聯用拉米伕定治療慢性乙型肝炎(CHB)的療效。方法：選擇68例CHB患者分為A、B兩組,A組38例採用阿德福韋酯聯閤拉米伕定治療1年；B組單用阿德福韋酯治療1年,拉米伕定100 mg,阿德福韋酯10 mg,均1次/d。結果：在治療初期單用ADV或與LAM聯用,均抑製病毒均有效,若長期服用,兩藥聯用效果更好。結論：拉米伕定聯閤阿德福韋酯是CHB較好的治療方案。
목적：관찰아덕복위지련용랍미부정치료만성을형간염(CHB)적료효。방법：선택68례CHB환자분위A、B량조,A조38례채용아덕복위지연합랍미부정치료1년；B조단용아덕복위지치료1년,랍미부정100 mg,아덕복위지10 mg,균1차/d。결과：재치료초기단용ADV혹여LAM련용,균억제병독균유효,약장기복용,량약련용효과경호。결론：랍미부정연합아덕복위지시CHB교호적치료방안。
Objective:To observe the efficacy of adefovir(ADV) combined with lamivudine(LAM) in treatment of chronic hepatitis. Methods:Sixty-eight patients with chronic hepatitis were randomly divided into A group and B group. Patients in A group were subjected to ADV and LAM, while patients in B group were subjected to ADV alone, LAM:100 mg/d, ADV:10 mg/day. Results:The total effective rates of the two groups showed no significant difference, but with the prolongation of time, the rate of obvious improvement of A group was higher than B group (P<0.01). Conclusion:ADV combined with LAM is rapid, safe and effective in the treatment of chronic hepatitis.
