中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2013年
7期
1214-1215
,共2页
阿托伐他汀联合替罗非班%急性心肌梗死
阿託伐他汀聯閤替囉非班%急性心肌梗死
아탁벌타정연합체라비반%급성심기경사
Effect of Atorvastatin Combined with tirofiban%Acute myocardial infarction
目的：研究利用阿托伐他汀联合替罗非班治疗急性心肌梗死(AMI)的临床表现、病理分析、治疗手段以及预后的影响因素。方法：将120例AMI的患者随机的分为两组，每组60例。观察组采用常规药物治疗加用阿托伐他汀联合替罗非班进行治疗，观察组每例患者需给予40mg的阿托伐他汀钙进行顿服，每晚需要以0.15μg/(kg·min)的速率维持40mg替罗非班静脉注射。对照组采用常规治疗。结果：共120例患者在进行了长达6个月的治疗后，达到缓解的有14例，占17.2%。达到部分缓解的有26例，占55.3%，无变化的有20例，占24.1%，恶化的有4例，占5.1%。治疗的总有效率达72.3%。在治疗之后的随访阶段，随访6个月~2年。6个月内患者存活率100%。结论：观察组在加服了阿托伐他汀联合替罗非班后，治疗后的生命体征的指标变化较对照组提高更大。加服阿托伐他汀联合替罗非班对AMI的患者的治疗比常规的治疗效果更好，并且能够明显改善患者的心脏功能。
目的：研究利用阿託伐他汀聯閤替囉非班治療急性心肌梗死(AMI)的臨床錶現、病理分析、治療手段以及預後的影響因素。方法：將120例AMI的患者隨機的分為兩組，每組60例。觀察組採用常規藥物治療加用阿託伐他汀聯閤替囉非班進行治療，觀察組每例患者需給予40mg的阿託伐他汀鈣進行頓服，每晚需要以0.15μg/(kg·min)的速率維持40mg替囉非班靜脈註射。對照組採用常規治療。結果：共120例患者在進行瞭長達6箇月的治療後，達到緩解的有14例，佔17.2%。達到部分緩解的有26例，佔55.3%，無變化的有20例，佔24.1%，噁化的有4例，佔5.1%。治療的總有效率達72.3%。在治療之後的隨訪階段，隨訪6箇月~2年。6箇月內患者存活率100%。結論：觀察組在加服瞭阿託伐他汀聯閤替囉非班後，治療後的生命體徵的指標變化較對照組提高更大。加服阿託伐他汀聯閤替囉非班對AMI的患者的治療比常規的治療效果更好，併且能夠明顯改善患者的心髒功能。
목적：연구이용아탁벌타정연합체라비반치료급성심기경사(AMI)적림상표현、병리분석、치료수단이급예후적영향인소。방법：장120례AMI적환자수궤적분위량조，매조60례。관찰조채용상규약물치료가용아탁벌타정연합체라비반진행치료，관찰조매례환자수급여40mg적아탁벌타정개진행돈복，매만수요이0.15μg/(kg·min)적속솔유지40mg체라비반정맥주사。대조조채용상규치료。결과：공120례환자재진행료장체6개월적치료후，체도완해적유14례，점17.2%。체도부분완해적유26례，점55.3%，무변화적유20례，점24.1%，악화적유4례，점5.1%。치료적총유효솔체72.3%。재치료지후적수방계단，수방6개월~2년。6개월내환자존활솔100%。결론：관찰조재가복료아탁벌타정연합체라비반후，치료후적생명체정적지표변화교대조조제고경대。가복아탁벌타정연합체라비반대AMI적환자적치료비상규적치료효과경호，병차능구명현개선환자적심장공능。
Objective:To study the effect of Atorvastatin Combined with tirofiban in the treatment of acute myocardial infarction clinical manifestation,pathological analysis,treatment and prognostic factors.Methods:120 cases of acute myocardial infarction patients were randomly divided into two groups,60 cases in each group.The observation group was treated with conventional medical therapy with Atorvastatin Combined with tirofiban treatment,the observation group each patient should be given 40mg of atorvastatin calcium were taken at night,with 0.15μg/(kg?min) rate to maintain the 40mg tirofiban intravenous injection.The control group was treated with routine treatment.Results:A total of 120 cases of patients for 6 months after treatment,14 cases achieved remission,17.2%.Achieved a partial response with 26 cases,accounting for 55.3%,with no change in 20 cases,accounting for 24.1%,the deterioration of the 4 cases,5.1%.Treatment the total effective rate was 72.3%.After treatment,the follow-up phase,the short follow-up time was 6 months,for a maximum of 2 years.In six months the productivity of 100%patients.Conclusion:In the observation group and taking atorvastatin combined with tirofiban,after treatment of the vital signs of the indicator changes than the control group improved more.Plus Atorvastatin Combined with tirofiban on acute myocardial infarction in patients with treatment than conventional treatment effect is better,and can obviously improve the cardiac function in patients with.
