CAJ | 학술논문

目的：：探讨孟鲁司特治疗小儿轻中度持续哮喘的临床疗效，为临床治疗提供参考依据。方法：选取我院门诊收治的200例轻中度持续哮喘患儿，采用随机对照方法将其分为观察组和对照组，每组各100例。对照组给予常规氧气吸入、雾化、抗感染等对症支持治疗，观察组在此基础上加用孟鲁司特，比较两组患儿临床疗效、临床症状评分及肺功能指标变化。结果：观察组总有效率显著高于对照组，差异有统计学意义(P<0.05)；两组患儿哮鸣音、喘息、咳嗽症状评分均显著改善(P<0.05)，且两组治疗后各临床症状评分相比，差异有统计学意义(P<0.05)；两组患儿肺功能指标FVC、FEV1及FEV1/FVC较治疗前相比均显著改善(P<0.05)，且两组治疗后肺功能指标相比，差异有统计学意义(P<0.05)。结论：孟鲁司特治疗小儿轻中度持续哮喘效果显著，可明显改善患儿肺功能，值得在临床上应用和推广。
목적：：탐토맹로사특치료소인경중도지속효천적림상료효，위림상치료제공삼고의거。방법：선취아원문진수치적200례경중도지속효천환인，채용수궤대조방법장기분위관찰조화대조조，매조각100례。대조조급여상규양기흡입、무화、항감염등대증지지치료，관찰조재차기출상가용맹로사특，비교량조환인림상료효、림상증상평분급폐공능지표변화。결과：관찰조총유효솔현저고우대조조，차이유통계학의의(P<0.05)；량조환인효명음、천식、해수증상평분균현저개선(P<0.05)，차량조치료후각림상증상평분상비，차이유통계학의의(P<0.05)；량조환인폐공능지표FVC、FEV1급FEV1/FVC교치료전상비균현저개선(P<0.05)，차량조치료후폐공능지표상비，차이유통계학의의(P<0.05)。결론：맹로사특치료소인경중도지속효천효과현저，가명현개선환인폐공능，치득재림상상응용화추엄。
Objective:To investigate clinical curative effect of montelukast in treatment of children with mild-to-moderate continuous asthma,provide a reference basis for clinical treatment.Methods:200 cases were divided into two groups.The control group conventional treatment of oxygen inhalation, atomization, resistance to infection,support therapy,, the observation group was added with montelukast, compared two groups of curative effect,clinical symptom scores and lung function index.Results:the observation group the total effective rate was significantly higher than that of control group(P<0.05);two groups of children with wheezing sound, breathing, cough symptom scores were significantly improved (P<0.05), and compared the two groups after treatment the clinical symptom scores, the difference was statistically significant (P<0.05);Moderate;lung function index was compared before treatment were significantly improved (P<0.05), and lung function index of the two groups after treatment compared with significant difference (P<0.05). Conclusion:Montelukast treatment of children with mild-to-moderate asthma continuous effect significantly,can significantly improve the pulmonary function in children with, is worth promoting.