中国感染控制杂志
中國感染控製雜誌
중국감염공제잡지
CHINESE JOURNAL OF INFECTION CONTROL
2014年
5期
274-276
,共3页
刘兴态%张艳%陈静%郑霞
劉興態%張豔%陳靜%鄭霞
류흥태%장염%진정%정하
降钙素原%D-二聚体%脓毒血症%APACHEⅡ评分%感染%预后
降鈣素原%D-二聚體%膿毒血癥%APACHEⅡ評分%感染%預後
강개소원%D-이취체%농독혈증%APACHEⅡ평분%감염%예후
procalcitonin%D-dimer%sepsis%APACHE II score%infection%prognosis
目的:探讨血降钙素原、D-二聚体检测对脓毒血症患者预后判断的临床价值。方法将68例脓毒血症患者按预后分为生存组和死亡组,比较两组间血降钙素原、D-二聚体水平并根据患者病情计算急性生理与慢性健康状况评分(APACHEⅡ),判断各指标对脓毒血症患者预后的预测价值。结果68例脓毒血症患者,生存组28例,死亡组40例,病死率58.82%。两组降钙素原、D-二聚体水平及APACHEⅡ评分经统计学分析,差异均有统计学意义(均P<0.05),死亡组均显著高于生存组。降钙素原、D-二聚体水平与 APACHEⅡ评分存在明显正相关性(P<0.05)。结论降钙素原、D-二聚体水平与 APACHEⅡ评分可用于评估脓毒血症患者病情,并作为预后预测的依据。
目的:探討血降鈣素原、D-二聚體檢測對膿毒血癥患者預後判斷的臨床價值。方法將68例膿毒血癥患者按預後分為生存組和死亡組,比較兩組間血降鈣素原、D-二聚體水平併根據患者病情計算急性生理與慢性健康狀況評分(APACHEⅡ),判斷各指標對膿毒血癥患者預後的預測價值。結果68例膿毒血癥患者,生存組28例,死亡組40例,病死率58.82%。兩組降鈣素原、D-二聚體水平及APACHEⅡ評分經統計學分析,差異均有統計學意義(均P<0.05),死亡組均顯著高于生存組。降鈣素原、D-二聚體水平與 APACHEⅡ評分存在明顯正相關性(P<0.05)。結論降鈣素原、D-二聚體水平與 APACHEⅡ評分可用于評估膿毒血癥患者病情,併作為預後預測的依據。
목적:탐토혈강개소원、D-이취체검측대농독혈증환자예후판단적림상개치。방법장68례농독혈증환자안예후분위생존조화사망조,비교량조간혈강개소원、D-이취체수평병근거환자병정계산급성생리여만성건강상황평분(APACHEⅡ),판단각지표대농독혈증환자예후적예측개치。결과68례농독혈증환자,생존조28례,사망조40례,병사솔58.82%。량조강개소원、D-이취체수평급APACHEⅡ평분경통계학분석,차이균유통계학의의(균P<0.05),사망조균현저고우생존조。강개소원、D-이취체수평여 APACHEⅡ평분존재명현정상관성(P<0.05)。결론강개소원、D-이취체수평여 APACHEⅡ평분가용우평고농독혈증환자병정,병작위예후예측적의거。
Objective To evaluate the clinical value of plasma procalcitonin and D-dimer measurements in estima-ting the prognosis of patients with sepsis.Methods According to prognosis,68 patients with sepsis were divided in-to survival group and death group,levels of procalcitonin and D-dimer,and acute physiology and chronic health eval-uation II (APACHE II)of two groups of patients were compared,predictive value of above markers in estimating the prognosis of patients with sepsis were evaluated.Results Of 68 patients with sepsis,28 survived and 40 died, mortality was 58.82%.There were significant differences in levels of procalcitonin and D-dimer,as well as APACHE II between two groups(both P<0.05),death group were all higher than survival group.Procalcitonin and D-dimer level were positively correlated with APACHE II score(P<0.05).Conclusion Procalcitonin,D-dimer level and APACHE II score can be used to evaluate condition of patients with sepsis as well as the prognosis of dis-ease.