中国感染控制杂志
中國感染控製雜誌
중국감염공제잡지
CHINESE JOURNAL OF INFECTION CONTROL
2014年
5期
271-273
,共3页
SIRS评分%全身炎症反应综合征%降钙素原%血流感染%诊断%预后%医院感染
SIRS評分%全身炎癥反應綜閤徵%降鈣素原%血流感染%診斷%預後%醫院感染
SIRS평분%전신염증반응종합정%강개소원%혈류감염%진단%예후%의원감염
systemic inflammatory response syndrome score%procalcitonin%bloodstream infection%diagnosis%prognosis%healthcare-associated infection
目的：探讨血流细菌感染患者血清中降钙素原(PCT)和患者全身炎症反应综合征(SIRS)评分的相关性。方法选择某院2012年1-12月收治的96例血流细菌感染患者作为实验组,按 SIRS评分将患者分为 A、B、C 3组；选择同期84例非细菌感染性疾病住院患者作为对照组,检测各组患者 PCT 水平,并对 PCT 水平和 SIRS评分进行相关性分析。结果实验组96例血流细菌感染患者,死亡7例(7.29%),其中B组死亡4例,C组死亡3例；对照组无死亡病例。对照组以及实验组中 A、B、C组 PCT水平分别为(0.28±0.09)ng/mL、(0.63±0.13)ng/mL、(3.68±1.01)ng/mL、(7.45±1.53)ng/mL,各组间PCT水平比较,差异有统计学意义(P<0.01)；4组间两两比较,差异均有统计学意义(均P<0.001)。对血流细菌感染组患者PCT水平与 SIRS评分进行 Spearman相关性分析,相关系数r=0.874(P<0.001),可认为患者血清中PCT水平与 SIRS评分呈正相关关系。结论血流细菌感染患者血清中PCT水平与 SIRS评分呈正相关,患者血清PCT水平和 SIRS评分可作为血流细菌感染患者病情危重程度和预后评估有意义的两项指标。
目的：探討血流細菌感染患者血清中降鈣素原(PCT)和患者全身炎癥反應綜閤徵(SIRS)評分的相關性。方法選擇某院2012年1-12月收治的96例血流細菌感染患者作為實驗組,按 SIRS評分將患者分為 A、B、C 3組；選擇同期84例非細菌感染性疾病住院患者作為對照組,檢測各組患者 PCT 水平,併對 PCT 水平和 SIRS評分進行相關性分析。結果實驗組96例血流細菌感染患者,死亡7例(7.29%),其中B組死亡4例,C組死亡3例；對照組無死亡病例。對照組以及實驗組中 A、B、C組 PCT水平分彆為(0.28±0.09)ng/mL、(0.63±0.13)ng/mL、(3.68±1.01)ng/mL、(7.45±1.53)ng/mL,各組間PCT水平比較,差異有統計學意義(P<0.01)；4組間兩兩比較,差異均有統計學意義(均P<0.001)。對血流細菌感染組患者PCT水平與 SIRS評分進行 Spearman相關性分析,相關繫數r=0.874(P<0.001),可認為患者血清中PCT水平與 SIRS評分呈正相關關繫。結論血流細菌感染患者血清中PCT水平與 SIRS評分呈正相關,患者血清PCT水平和 SIRS評分可作為血流細菌感染患者病情危重程度和預後評估有意義的兩項指標。
목적：탐토혈류세균감염환자혈청중강개소원(PCT)화환자전신염증반응종합정(SIRS)평분적상관성。방법선택모원2012년1-12월수치적96례혈류세균감염환자작위실험조,안 SIRS평분장환자분위 A、B、C 3조；선택동기84례비세균감염성질병주원환자작위대조조,검측각조환자 PCT 수평,병대 PCT 수평화 SIRS평분진행상관성분석。결과실험조96례혈류세균감염환자,사망7례(7.29%),기중B조사망4례,C조사망3례；대조조무사망병례。대조조이급실험조중 A、B、C조 PCT수평분별위(0.28±0.09)ng/mL、(0.63±0.13)ng/mL、(3.68±1.01)ng/mL、(7.45±1.53)ng/mL,각조간PCT수평비교,차이유통계학의의(P<0.01)；4조간량량비교,차이균유통계학의의(균P<0.001)。대혈류세균감염조환자PCT수평여 SIRS평분진행 Spearman상관성분석,상관계수r=0.874(P<0.001),가인위환자혈청중PCT수평여 SIRS평분정정상관관계。결론혈류세균감염환자혈청중PCT수평여 SIRS평분정정상관,환자혈청PCT수평화 SIRS평분가작위혈류세균감염환자병정위중정도화예후평고유의의적량항지표。
Objective To evaluate the correlation between serum procalcitonin concentration and systemic inflam-matory response syndrome (SIRS)score in patients with bacterial bloodstream infection.Methods In January-De-cember,2012,96 patients with bacterial bloodstream infection in a hospital were selected as trial group,and these patients were divided into three groups(group A,B and C)according to SIRS score;84 patients without bacterial in-fection was as control group,PCT concentration of all patients were detected,and the correlation between PCT con-centration and SIRS score was analyzed.Results Among 96 patients with bacterial bloodstream infection,7 (7.29%)died (4 were in group B and 3 in group C);there was no death case in control group.PCT concentration in control group,group A,B and C of trial group were (0.28±0.09)ng/mL,(0.63±0.13)ng/mL,(3.68±1.01)ng/mL,and(7.45±1.53)ng/mL,respectively,the difference between each group was significant(P<0.01).Pairwise comparison of four groups showed statistical difference (P<0.001).Spearman correlation analysis on PCT concen-tration and SIRS score was conducted,correlation coefficient r=0.874(P<0.001)suggested positive correlation be-tween serum PCT concentration and SIRS score.Conclusion PCT concentration in patients with bacterial blood-stream infection and SIRS score is positively correlated,PCT concentration and SIRS score can be used as two mark-ers for assessing the extent and prognosis of bacterial bloodstream infection.
