山西中医学院学报
山西中醫學院學報
산서중의학원학보
JOURNAL OF SHANXI COLLEGE OF TRADITIONAL CHINESE MEDICINE
2013年
6期
21-22,25
,共3页
吴秋玲%李建宽%刘竺华%李朝喧
吳鞦玲%李建寬%劉竺華%李朝喧
오추령%리건관%류축화%리조훤
抗血管生成%藤梨根%血管内皮细胞%肿瘤
抗血管生成%籐梨根%血管內皮細胞%腫瘤
항혈관생성%등리근%혈관내피세포%종류
antiangiogenesis%Radix Actinidiae%vascular endothelial cell%tumor
目的:研究藤梨根对人脐静脉血管内皮细胞(HUVECS)增殖作用的影响,从抑制血管生成途径探讨藤梨根抗肿瘤的作用机制。方法:运用MTT法,观察高、中、低剂量藤梨根含药血清对HUVECS细胞活力的影响。结果:与对照组比较,藤梨根高、中剂量血清组OD值降低,差异有统计学意义(P<0.05)。结论:藤梨根含药血清有一定的抑制人脐静脉血管内皮细胞增殖的作用。
目的:研究籐梨根對人臍靜脈血管內皮細胞(HUVECS)增殖作用的影響,從抑製血管生成途徑探討籐梨根抗腫瘤的作用機製。方法:運用MTT法,觀察高、中、低劑量籐梨根含藥血清對HUVECS細胞活力的影響。結果:與對照組比較,籐梨根高、中劑量血清組OD值降低,差異有統計學意義(P<0.05)。結論:籐梨根含藥血清有一定的抑製人臍靜脈血管內皮細胞增殖的作用。
목적:연구등리근대인제정맥혈관내피세포(HUVECS)증식작용적영향,종억제혈관생성도경탐토등리근항종류적작용궤제。방법:운용MTT법,관찰고、중、저제량등리근함약혈청대HUVECS세포활력적영향。결과:여대조조비교,등리근고、중제량혈청조OD치강저,차이유통계학의의(P<0.05)。결론:등리근함약혈청유일정적억제인제정맥혈관내피세포증식적작용。
Objective:To observe the effect of Radix Actinidiae on proliferative effect of human umbilical vein endothelial cells(HUVECS),explore anti-tumor mechanism of Radix Actinidiae from the channel of inhibiting angiogenesis. Methods:MTT method was used to observe the effects of high,middle,low dosage of Radix Actinidiae drug-containing serum on HUVECS viability. Results:Compared with control group,OD value of high,middle dosage of Radix Actinidiae drug-con-taining serum group was significantly declined (P<0.05). Conclusion:Radix Actinidiae drug-containing serum has certain inhibitive effect on proliferation of human umbilical vein endothelial cells.