内蒙古医科大学学报
內矇古醫科大學學報
내몽고의과대학학보
Journal of Inner Mongolia Medical University
2013年
6期
475-478
,共4页
放疗%化疗%宫颈癌
放療%化療%宮頸癌
방료%화료%궁경암
radiotherapy%chemotherapy%cervical carcinoma
目的：研究放疗同步联合化疗治疗中晚期宫颈癌的临床治疗效果。方法：选择2007-09~2009-09共治疗的84例宫颈癌病人,随机分为观察组(同步放化疗组)41例,对照组(单纯放疗组)43例,两组病人均行根治性放疗,观察组41例放疗的同时加化疗方案,顺铂40 mg/m2静脉滴注,同时配合保肝、激素、水化治疗,并对两组的治疗效果进行比较。结果：全组病人均顺利完成本实验的放、化疗程,观察组3mo总有效率为90.24%(37/41),对照组3mo总有效率为72.1%(31/43),两组之间比较差异具有统计学意义(x2=4.484,P<0.05)；观察组1a、3a生存率分别为97.56%(40/41)、78.05%(32/41),对照组1a、3a 生存率分别为81.39%(35/43)、55.81%(24/43),两组之间比较差异具有统计学意义(x2=4.168,P<0.05；x2=4.669,P<0.05)。结论：放疗同步联合化疗治疗中晚期宫颈癌疗效显著,是理想的中晚期宫颈癌治疗方法。
目的：研究放療同步聯閤化療治療中晚期宮頸癌的臨床治療效果。方法：選擇2007-09~2009-09共治療的84例宮頸癌病人,隨機分為觀察組(同步放化療組)41例,對照組(單純放療組)43例,兩組病人均行根治性放療,觀察組41例放療的同時加化療方案,順鉑40 mg/m2靜脈滴註,同時配閤保肝、激素、水化治療,併對兩組的治療效果進行比較。結果：全組病人均順利完成本實驗的放、化療程,觀察組3mo總有效率為90.24%(37/41),對照組3mo總有效率為72.1%(31/43),兩組之間比較差異具有統計學意義(x2=4.484,P<0.05)；觀察組1a、3a生存率分彆為97.56%(40/41)、78.05%(32/41),對照組1a、3a 生存率分彆為81.39%(35/43)、55.81%(24/43),兩組之間比較差異具有統計學意義(x2=4.168,P<0.05；x2=4.669,P<0.05)。結論：放療同步聯閤化療治療中晚期宮頸癌療效顯著,是理想的中晚期宮頸癌治療方法。
목적：연구방료동보연합화료치료중만기궁경암적림상치료효과。방법：선택2007-09~2009-09공치료적84례궁경암병인,수궤분위관찰조(동보방화료조)41례,대조조(단순방료조)43례,량조병인균행근치성방료,관찰조41례방료적동시가화료방안,순박40 mg/m2정맥적주,동시배합보간、격소、수화치료,병대량조적치료효과진행비교。결과：전조병인균순리완성본실험적방、화료정,관찰조3mo총유효솔위90.24%(37/41),대조조3mo총유효솔위72.1%(31/43),량조지간비교차이구유통계학의의(x2=4.484,P<0.05)；관찰조1a、3a생존솔분별위97.56%(40/41)、78.05%(32/41),대조조1a、3a 생존솔분별위81.39%(35/43)、55.81%(24/43),량조지간비교차이구유통계학의의(x2=4.168,P<0.05；x2=4.669,P<0.05)。결론：방료동보연합화료치료중만기궁경암료효현저,시이상적중만기궁경암치료방법。
Objective:To investigate efficacy of radiotherapy combined with chemotherapy in treatment of advanced cervical carcinoma. Methods:All of the 84 cases patients with advanced stage cervical carcinoma were divided randomly into 41 cases in observe group ( radiotherapy combined with chemotherapy group ) and 43 cases in control group ( radiotherapy alone group ) September 2007 to September 2009, all of 84 cases patients in two groups received radical radiotherapy, 41 cases in observe group were received chemotherapy concurrently, cisplatin 40 mg/m2 drop by vein, and were treated by protection of liver、hormones、hydration,effects were analyzed. Results:All of the 84 cases were successfully completed treatment by chemotherapy and ( or ) radiotherapy, the 3-months total effective rates in observe group were 90 . 24%( 37/41 ) , the 3-months total effective rates in control group were 72. 1%(31/43),there were obvious distinction between two groups(x2=4. 484,P<0. 05);the 1-year、3-year survival rates of patients in observe group were 95. 1(39/41)、73. 2%(30/41)re-spectively,the 1-year、3-year survival rates of patients in control group were 83. 7(36/43)、58. 1%(25/43) respectively, there were obvious distinction between two groups ( x2=4. 168, P<0. 05;x2=4. 669,P<0. 05). Conclusion:Effects of radiotherapy combined with chemotherapy in treatment of advanced cervical carcinoma are obvious, which can be the ideal method for advanced cervical carcinoma patients.
