内蒙古医科大学学报
內矇古醫科大學學報
내몽고의과대학학보
Journal of Inner Mongolia Medical University
2013年
6期
459-462
,共4页
粪肠球菌%屎肠球菌%耐药性监测%抗菌药物
糞腸毬菌%屎腸毬菌%耐藥性鑑測%抗菌藥物
분장구균%시장구균%내약성감측%항균약물
Enterococcus faecalis%Enterococcus faecium%antibiotic resistance surveillance%antibi-otics
目的：了解粪肠球菌和屎肠球菌对抗菌药物的耐药性，为临床提供治疗依据。方法：对住院及门诊病人送检样本中培养分离出316株肠球菌(粪肠球菌126株，屎肠球菌190株)的感染分布与耐药情况进行分析。采用稀释法进行药物敏感试验，结果按美国临床实验室标准化研究所标准判定。结果：屎肠球菌对青霉素G的耐药率最高(93.7%)，其次为红霉素、氨苄西林和环丙沙星。粪肠球菌对奎奴普丁/达福普汀耐药率最高为(74%)，其次为四环素、红霉素和环丙沙星。粪肠球菌和屎肠球菌对利奈唑胺和万古霉素的耐药率均低于(2%)，替考拉宁的耐药率最低均为(0)。结论：粪肠球菌和屎肠球菌对不同抗菌药物的耐药率有较大差异，在抗感染治疗前应先做细菌培养和药物敏感试验，依据报告结果合理选用抗菌药物。
目的：瞭解糞腸毬菌和屎腸毬菌對抗菌藥物的耐藥性，為臨床提供治療依據。方法：對住院及門診病人送檢樣本中培養分離齣316株腸毬菌(糞腸毬菌126株，屎腸毬菌190株)的感染分佈與耐藥情況進行分析。採用稀釋法進行藥物敏感試驗，結果按美國臨床實驗室標準化研究所標準判定。結果：屎腸毬菌對青黴素G的耐藥率最高(93.7%)，其次為紅黴素、氨芐西林和環丙沙星。糞腸毬菌對奎奴普丁/達福普汀耐藥率最高為(74%)，其次為四環素、紅黴素和環丙沙星。糞腸毬菌和屎腸毬菌對利奈唑胺和萬古黴素的耐藥率均低于(2%)，替攷拉寧的耐藥率最低均為(0)。結論：糞腸毬菌和屎腸毬菌對不同抗菌藥物的耐藥率有較大差異，在抗感染治療前應先做細菌培養和藥物敏感試驗，依據報告結果閤理選用抗菌藥物。
목적：료해분장구균화시장구균대항균약물적내약성，위림상제공치료의거。방법：대주원급문진병인송검양본중배양분리출316주장구균(분장구균126주，시장구균190주)적감염분포여내약정황진행분석。채용희석법진행약물민감시험，결과안미국림상실험실표준화연구소표준판정。결과：시장구균대청매소G적내약솔최고(93.7%)，기차위홍매소、안변서림화배병사성。분장구균대규노보정/체복보정내약솔최고위(74%)，기차위사배소、홍매소화배병사성。분장구균화시장구균대리내서알화만고매소적내약솔균저우(2%)，체고랍저적내약솔최저균위(0)。결론：분장구균화시장구균대불동항균약물적내약솔유교대차이，재항감염치료전응선주세균배양화약물민감시험，의거보고결과합리선용항균약물。
Objective:To get knowledge of antimicrobial resistance of Enterococcus Faecalis and Enterococcus Faecium to antibiotics, and further provide basis for treatment. Methods:316 strians of enterococci composed of 126 strains of enterococcus faecalis and 190 strains of enterococcus faecium were cultured and isolated from samples of inpatients and outpatients,and distribution of infection and antimicrobial resistance were analyzed. Agar dilution method was used to do antibiotic susceptibility test,and the results were determined based on the standard of Clinical and Laboratory Standard Institute ( CLSI 2012 ) . Results:The resistance rate of enterococcus faecium to penicillin G ( 93 . 7%) is the highest among all of the antimicrobial tested, followed by erythromycin, ampicillin, ciprofloxacin. The resistance rate of enterococcus faecium to quinupristin/dalfopristin(74%) was the highest among all of the antimicrobials tested,followed by tetracycline,erythromycin and ciprofloxacin. The resistance rate of enterococcus faecalis and enterococcus faecium to linezolid and vancomycin were all lower than 2%,and that to teicoplanin was the lowest(0%) . Conclusions:The resistance rate of enterococcus faecalis and enterococcus faecium to different kinds of antibiotics differed much. Bacterial culture and antimicrobial susceptibility tests should be performed before anti-infection treatment initiated and reasonable antibiotics be selected based on antimicrobial susceptibility test report.
