内蒙古医科大学学报
內矇古醫科大學學報
내몽고의과대학학보
Journal of Inner Mongolia Medical University
2013年
6期
442-445
,共4页
绝经后骨质疏松%去卵巢大鼠%淫羊藿提取物%骨密度
絕經後骨質疏鬆%去卵巢大鼠%淫羊藿提取物%骨密度
절경후골질소송%거란소대서%음양곽제취물%골밀도
postmenopausal osteoporosis%ovariectomized rats%epimedium extract%bone mineral density
目的：研究淫羊藿提取物对去卵巢大鼠骨密度、骨重量的影响,探讨中医肾主骨理论。方法：取84只雌性大鼠随机分成假手术组、模型组、己烯雌酚组、骨疏康组、淫羊藿提取物高、中、低剂量组7组,每组12只。造模成功后,饲养90 d,开始灌胃90 d后,检测离体骨骨密度、骨重量。结论：淫羊藿提取物可提高去卵巢大鼠离体骨骨密度、增加离体骨湿重、干重。对实验大鼠去卵巢所致骨质疏松症有明显的治疗作用。
目的：研究淫羊藿提取物對去卵巢大鼠骨密度、骨重量的影響,探討中醫腎主骨理論。方法：取84隻雌性大鼠隨機分成假手術組、模型組、己烯雌酚組、骨疏康組、淫羊藿提取物高、中、低劑量組7組,每組12隻。造模成功後,飼養90 d,開始灌胃90 d後,檢測離體骨骨密度、骨重量。結論：淫羊藿提取物可提高去卵巢大鼠離體骨骨密度、增加離體骨濕重、榦重。對實驗大鼠去卵巢所緻骨質疏鬆癥有明顯的治療作用。
목적：연구음양곽제취물대거란소대서골밀도、골중량적영향,탐토중의신주골이론。방법：취84지자성대서수궤분성가수술조、모형조、기희자분조、골소강조、음양곽제취물고、중、저제량조7조,매조12지。조모성공후,사양90 d,개시관위90 d후,검측리체골골밀도、골중량。결론：음양곽제취물가제고거란소대서리체골골밀도、증가리체골습중、간중。대실험대서거란소소치골질소송증유명현적치료작용。
Objective:To Studying the effect of Epimedium Extract on bone mineral density、bone weight of some ovariectomized rats,exploring the theory of TCM kidneys bone. Methods:We selected 84 female rats in the study,they were randomly divided into 7 groups:shamed operations group、model group、diethylstilbestrol group、gushukang group 、Epimedium Extract at high 、medium and low dose groups,every group had 12 rats. After success of modeling, we fed rats for 90 days under the same situation and then gavaged for 90 days, detected in vitro bone mineral density, bone weight. Conclusion:The results indicated that the Epimedium Extract could improve ovariectomized rats in vitro bone mineral density, increased in vitro bone wet weight、dry weight. It had a significant therapeutic effect on osteoporosis caused by ovariectomized rats.
