CAJ | 학술논문

[目的]评估全身磁共振成像（WB-MRI）包括全身弥散成像（WB-DWI）与全身CT 在恶性黑色素瘤分级能力的差异，并进一步评价WB-DWI在病变检出方面与WB-M RI比较的差异。[方法]WB-DWI用于23例病患的胸、腹、盆扫描，并全部进行包括C T、WB-M RI检查，全部病例均经过组织学确诊恶性黑色素瘤。在M RI检查之前及随访中均采用CT作为参照。[结果]WB-MRI及WB-DWI分别检查到345和302个病灶。CT 检查出397个病灶，在不同部位WB-M RI和WB-DWI 检查敏感性存在显著差异，肺部转移灶WB-M RI的检出率为38（个）灶/17例，WB-DWI为28（个）灶/14例，CT 为60（个）灶/21例；骨的检出率 WB-MRI和WB-DWI均为56（个）灶/12例，而C T为42（个）灶/8例。[结论]WB-M RI尚不能取代C T 来进行恶性黑色素瘤分级，特别是胸部；对于骨转移病灶而言，WB-M RI具有优势，在进行M RI检查时必须同时使用WB-DWI和WB-M RI序列才能够达到病灶检出的要求。
[목적]평고전신자공진성상（WB-MRI）포괄전신미산성상（WB-DWI）여전신CT 재악성흑색소류분급능력적차이，병진일보평개WB-DWI재병변검출방면여WB-M RI비교적차이。[방법]WB-DWI용우23례병환적흉、복、분소묘，병전부진행포괄C T、WB-M RI검사，전부병례균경과조직학학진악성흑색소류。재M RI검사지전급수방중균채용CT작위삼조。[결과]WB-MRI급WB-DWI분별검사도345화302개병조。CT 검사출397개병조，재불동부위WB-M RI화WB-DWI 검사민감성존재현저차이，폐부전이조WB-M RI적검출솔위38（개）조/17례，WB-DWI위28（개）조/14례，CT 위60（개）조/21례；골적검출솔 WB-MRI화WB-DWI균위56（개）조/12례，이C T위42（개）조/8례。[결론]WB-M RI상불능취대C T 래진행악성흑색소류분급，특별시흉부；대우골전이병조이언，WB-M RI구유우세，재진행M RI검사시필수동시사용WB-DWI화WB-M RI서렬재능구체도병조검출적요구。
[Objective] To compare the value of whole-body diffusion imaging(WB-DWI) vs .computed tomo-graphy(CT) for the staging of malignant melanoma ,and further compare the value of WB-DWI and whole magnet-ic resonance imaging(WB-MRI) for the detection of lesions .[Methods]WB-MRI was used to scan the chest ,abdo-men ,and pelvis of 23 patients .CT and WB-MRI were performed in all patients .All cases were histologically con-firmed as malignant melanoma .CT before and after MRI and clinical follow-up was taken as the reference .[Re-sults]WB-MRI and WB-DWI could detect 345 and 302 lesions ,respectively ,while CT could detect 397 lesions . There was significant difference in the sensitivity between WB-MRI and WB-DWI at different regions of the body . The detective rate of WB-MRI ,WB-DWI and CT for lung metastasis was 38 lesions/17 cases ,28 lesions/14 cases and 60 lesions/21 cases ,respectively .The detective rate of both WB-MRI and WB-DWI for bone metastasis was 56 lesions/12 cases ,while that of CT was 42 lesions/8 cases .[Conclusion]WB-MRI is still not ready to replace CT for the staging of malignant melanoma ,especially for chest .WB-MRI is advantageous for the detection of bone metastasis lesions .MRI combined with WB-DWI and WB-MRI sequence can detect the lesions .