CAJ | 학술논문

目的：探讨复发急性格林-巴利综合征（ GBS）的临床特点。方法选择收治的3例复发GBS的患者（均符合Asbury 1990年诊断标准），分析其诱因、发病过程、临床表现、肌电生理检查、脑脊液检查、治疗及预后等。结果经治疗3例中1例3个月恢复正常，1例5个月恢复正常，1例遗留肢体肌力减弱。结论复发GBS有发病急、进展快、病程长及病情重等特点，治疗目前仍以免疫球蛋白及血浆置换等方法为主，临床预后相对较好，但对于反复发作的GBS，亦可以遗留严重的神经功能损害。
목적：탐토복발급성격림-파리종합정（ GBS）적림상특점。방법선택수치적3례복발GBS적환자（균부합Asbury 1990년진단표준），분석기유인、발병과정、림상표현、기전생리검사、뇌척액검사、치료급예후등。결과경치료3례중1례3개월회복정상，1례5개월회복정상，1례유류지체기력감약。결론복발GBS유발병급、진전쾌、병정장급병정중등특점，치료목전잉이면역구단백급혈장치환등방법위주，림상예후상대교호，단대우반복발작적GBS，역가이유류엄중적신경공능손해。
Objective To explore the clinical feature of recurrent Guillain-Barre syndrome(GBS).Methods The predisposition , pathogenetic process , clinical manifestations , electrophysiologic examination , cerebrospinal fluid examination , therapeutic process and prognosis were analyzed in 3 patients with recurrent GBS in accord with diagnos-tic criteria of Asbury in 1990 .Results Complete recovery was abstained in one patient 3 months after treatment , and in one patient 5 months after treatment , and mild decrease of limbs muscle strength was left in one patient .Conclu-sion Recurrent GBS was characterized by acute onset ,rapid deterioration ,long and critical course .The main treat-ment included intravenous immunoglobulin or plasma exchange .Clinical prognosis was relatively good .But severe nerve function damage maybe leaved in the patients with repeated relapse of GBS .