CAJ | 학술논문

目的：探讨舍曲林联合丁螺环酮治疗抑郁症伴性功能障患者的临床疗效。方法将100例抑郁症伴性功能障碍患者随机分为两组，每组50例，两组均口服舍曲林治疗，观察组联合丁螺环酮合治疗，观察8周。采用汉密顿抑郁量表、抑郁自评量表评定抑郁状况，Olson婚姻质量问卷评定婚姻质量，性生活满意度量表评定性生活满意度。结果治疗后两组汉密顿抑郁量表、抑郁自评量表评分均较治疗前显著下降（P＜0．01），观察组较对照组下降更显著（P＜0．01）；两组Olson婚姻质量问卷评分均较治疗前显著升高（P＜0．01），观察组较对照组升高更显著（P＜0．01）；观察组性生活总满意率显著高于对照组（χ2＝7．48，P＜0．01）。结论舍曲林联合丁螺环酮治疗抑郁症伴性功能障患者效果显著，能显著提高患者的性生活满意度和婚姻质量，显著优于单用舍曲林治疗。
목적：탐토사곡림연합정라배동치료억욱증반성공능장환자적림상료효。방법장100례억욱증반성공능장애환자수궤분위량조，매조50례，량조균구복사곡림치료，관찰조연합정라배동합치료，관찰8주。채용한밀돈억욱량표、억욱자평량표평정억욱상황，Olson혼인질량문권평정혼인질량，성생활만의도량표평정성생활만의도。결과치료후량조한밀돈억욱량표、억욱자평량표평분균교치료전현저하강（P＜0．01），관찰조교대조조하강경현저（P＜0．01）；량조Olson혼인질량문권평분균교치료전현저승고（P＜0．01），관찰조교대조조승고경현저（P＜0．01）；관찰조성생활총만의솔현저고우대조조（χ2＝7．48，P＜0．01）。결론사곡림연합정라배동치료억욱증반성공능장환자효과현저，능현저제고환자적성생활만의도화혼인질량，현저우우단용사곡림치료。
Objective To explore the efficacy of sertraline combined with buspirone in depression with sex-ual dysfunction .Methods A total of 100 depression patients with sexual dysfunction were randomly as-signed to two groups of 50 ones each ,both groups took orally sertraline ,observation group was plus bus-pirone for 8 weeks . Depression status was assessed with the Hamilton Rating Scale for Depression (HRSD) and Self-rating Depression Scale (SDS) ,marital quality with the Olson Marital Quality Question-naire (ENRICH) ,and sexual satisfaction with the Sexual Satisfaction Scale (SSS) .Results After treat-ment the HRSD and SDS scores of both groups lowered more significantly compared with pre-treatment (P<0 .01) ,so did those in observation than in control group (P< 0 .01);the ENRICH scores of both groups heightened more significantly (P<0 .01) ,so did those in observation than in control group (P<0 .01);sexual satisfaction was significantly higher in observation than in control group (χ2 = 7 .48 , P<0 .01) .Conclusion Sertraline combined with buspirone has an evident effect in depression with sexual dys-function ,can notably improve sexual satisfaction and marital quality compared with single sertraline .