CAJ | 학술논문

目的：评价肝动脉化疗栓塞术（TACE）联合冷循环射频消融术（RFA）治疗肝脏肿瘤的临床疗效。方法61例肝脏肿瘤分为单纯TACE治疗组（34例）和TACE联合冷循环射频消融术治疗组（27例）。治疗后行DSA、CT、超声检查及血清甲胎蛋白（ AFP）测定。结果单纯TACE组肿瘤有效率、AFP下降率、1年生存率分别为52．9％、38．2％和48．4％，TACE＋RFA联合组分别为85．2％、59．3％和79．4％，两组比较差异有统计学意义（P＜0．05）。结论 TACE＋RFA较单纯TACE治疗中晚期肝癌效果好，是治疗中晚期肝癌的一种有效方法，有较高的临床推广价值。
목적：평개간동맥화료전새술（TACE）연합랭순배사빈소융술（RFA）치료간장종류적림상료효。방법61례간장종류분위단순TACE치료조（34례）화TACE연합랭순배사빈소융술치료조（27례）。치료후행DSA、CT、초성검사급혈청갑태단백（ AFP）측정。결과단순TACE조종류유효솔、AFP하강솔、1년생존솔분별위52．9％、38．2％화48．4％，TACE＋RFA연합조분별위85．2％、59．3％화79．4％，량조비교차이유통계학의의（P＜0．05）。결론 TACE＋RFA교단순TACE치료중만기간암효과호，시치료중만기간암적일충유효방법，유교고적림상추엄개치。
Objective To evaluate the clinical value of radiofrequency ablation (RFA) combined with transcatheter he-patic arterial chemoembolization ( TACE) on hepatic carcinoma .Methods 61 patients with primary liver cancer were divided into two groups:34 cases were treated with TACE alone and 27 cases were treated with TACE combined with RFA .To evaluate the ef-ficacy with DSA、CT、ultrasound and serum alpha-fetoprotein (AFP) after treatment.Results The tumor efficiency、relapse rate and 1-year survival rates of TACE group were 52.9%、38.2%、48.4%respectively,and those of the TACE +RFA combination group were 85.2%、59.3% and 79.4%respectively,and there was statistical differences between the two groups (P<0.05). Conclusion Compared with TACE ,TACE +RFA is effective for advanced liver cancer .It is an effective method for the treat-ment of advanced hepatocellular carcinoma ,and has high clinical value .