健康研究
健康研究
건강연구
HEALTH RESEARCH
2014年
1期
37-39,42
,共4页
细针穿刺细胞学%乳腺癌%定性诊断
細針穿刺細胞學%乳腺癌%定性診斷
세침천자세포학%유선암%정성진단
fine needle aspiration cytology%breast cancer%qualitative diagnosis
目的:探讨乳腺癌定性诊断中细针穿刺细胞学( Fine needle aspiration cytology ,FNAC)检查的临床应用价值。方法选择2011年1月至2012年12月期间我院诊治的可疑乳腺癌患者72例,将乳腺细针穿刺细胞学检查同超声检查和组织病理学诊断结果进行对比研究,评价乳腺癌定性诊断中细针穿刺细胞学检查的应用价值。结果行乳腺细针吸取细胞学检查72例可疑乳腺癌患者中,FNAC诊断为乳腺癌54例,直接行根治性手术,术后组织病理学诊断均为乳腺癌,假阳性率为0.00%(0/72),假阴性率为4.17%(3/72),特异性和敏感性分别为100.00%(15/15)和94.74%(54/57),总准确率95.83(69/72);与超声检查比较,FNAC检查在假阳性率和特异性方面无统计学意义(P>0.05),但假阴性率明显低于超声检查(χ2=4.143,P<0.05),FNAC检查的敏感性和总准确率明显高于超声检查(P<0.05)。结论 FNAC检查具有安全快速、经济方便、敏感性和准确率高等特点,可为乳腺癌患者术前诊断和手术治疗方式的选择提供依据,临床应用前景广阔。
目的:探討乳腺癌定性診斷中細針穿刺細胞學( Fine needle aspiration cytology ,FNAC)檢查的臨床應用價值。方法選擇2011年1月至2012年12月期間我院診治的可疑乳腺癌患者72例,將乳腺細針穿刺細胞學檢查同超聲檢查和組織病理學診斷結果進行對比研究,評價乳腺癌定性診斷中細針穿刺細胞學檢查的應用價值。結果行乳腺細針吸取細胞學檢查72例可疑乳腺癌患者中,FNAC診斷為乳腺癌54例,直接行根治性手術,術後組織病理學診斷均為乳腺癌,假暘性率為0.00%(0/72),假陰性率為4.17%(3/72),特異性和敏感性分彆為100.00%(15/15)和94.74%(54/57),總準確率95.83(69/72);與超聲檢查比較,FNAC檢查在假暘性率和特異性方麵無統計學意義(P>0.05),但假陰性率明顯低于超聲檢查(χ2=4.143,P<0.05),FNAC檢查的敏感性和總準確率明顯高于超聲檢查(P<0.05)。結論 FNAC檢查具有安全快速、經濟方便、敏感性和準確率高等特點,可為乳腺癌患者術前診斷和手術治療方式的選擇提供依據,臨床應用前景廣闊。
목적:탐토유선암정성진단중세침천자세포학( Fine needle aspiration cytology ,FNAC)검사적림상응용개치。방법선택2011년1월지2012년12월기간아원진치적가의유선암환자72례,장유선세침천자세포학검사동초성검사화조직병이학진단결과진행대비연구,평개유선암정성진단중세침천자세포학검사적응용개치。결과행유선세침흡취세포학검사72례가의유선암환자중,FNAC진단위유선암54례,직접행근치성수술,술후조직병이학진단균위유선암,가양성솔위0.00%(0/72),가음성솔위4.17%(3/72),특이성화민감성분별위100.00%(15/15)화94.74%(54/57),총준학솔95.83(69/72);여초성검사비교,FNAC검사재가양성솔화특이성방면무통계학의의(P>0.05),단가음성솔명현저우초성검사(χ2=4.143,P<0.05),FNAC검사적민감성화총준학솔명현고우초성검사(P<0.05)。결론 FNAC검사구유안전쾌속、경제방편、민감성화준학솔고등특점,가위유선암환자술전진단화수술치료방식적선택제공의거,림상응용전경엄활。
Objective To explore the clinical value of BFNAC in the diagnosis of breast cancer .Method 72 patients suspicious of breast cancer admitted to the hospital during the period from January ,2011 to December ,2012 were chosen as subjects of the study .Mammary gland fine needle puncture cytological examination with ultrasound was used and compared with histopathologic diagnosis research .The surgical treatment for breast cancer in the fine needle puncture cytological examination of application value was evaluated .Findings For the 72 patients suspected of breast cancer , mammary gland fine needle line absorbing cytology was used , 54 cases were diagnosed as cases of breast cancer by FNAC and radical surgery directly, postoperative histopathological diagnosis of breast cancer .The false positive rate was 0.00%(0/72), and the false negative rate was 4.17% (3/72).Specificity and sensitivity was 100.00% (15/15) and 94.74% (54/57) respectively, the total accuracy was 95.83%(69/72); there showed no statistical significance between ultrasound andFNAC check in terms of false positive rate and specificity (P >0.05), but the FNAC check the false negative rate wassignificantly lower than the ultrasound, showing statistical significance (χ2 =4.143, P <0.05).The sensitivity and thetotal accuracy of FNAC inspection was obviously higher than that of ultrasound .The difference has statistical significance(P <0.05).Conclusion FNAC check is found to be safe and fast, economical, convenient , of high sensitivity andaccuracy.It can be effective in preoperative diagnosis of breast cancer .