CAJ | 학술논문

目的：探讨老年慢性肾脏病（CKD）并发肾心综合征（RCS）的危险因素，为预防RCS提供参考。方法对2010年3月至2013年3月在解放军总医院住院治疗的222例老年CKD患者的临床资料进行回顾性分析。应用logistic回归分析筛选RCS发生的危险因素。结果老年慢性RCS的发生率为25.2%；单因素分析结果显示，年龄、肾功能分期、糖尿病史、高血压病史、贫血、营养不良与RCS发生有关，而性别、吸烟史、脑血管病史、CKD病程、血脂紊乱等因素与RCS发生无明显相关性（P＞0.05）；多因素logistic回归法分析表明，年龄、肾功能分期、糖尿病、高血压病史、贫血是RCS发生的独立危险因素。结论高龄（≥80岁）、肾功能3B期以上，伴有糖尿病、高血压病史和贫血的CKD患者发生RCS的风险大，应该特别重视对以上危险因素的评估和控制。
목적：탐토노년만성신장병（CKD）병발신심종합정（RCS）적위험인소，위예방RCS제공삼고。방법대2010년3월지2013년3월재해방군총의원주원치료적222례노년CKD환자적림상자료진행회고성분석。응용logistic회귀분석사선RCS발생적위험인소。결과노년만성RCS적발생솔위25.2%；단인소분석결과현시，년령、신공능분기、당뇨병사、고혈압병사、빈혈、영양불량여RCS발생유관，이성별、흡연사、뇌혈관병사、CKD병정、혈지문란등인소여RCS발생무명현상관성（P＞0.05）；다인소logistic회귀법분석표명，년령、신공능분기、당뇨병、고혈압병사、빈혈시RCS발생적독립위험인소。결론고령（≥80세）、신공능3B기이상，반유당뇨병、고혈압병사화빈혈적CKD환자발생RCS적풍험대，응해특별중시대이상위험인소적평고화공제。
Objective To investigate the related risk factors of renal-cardiac syndrome (RCS) in the elderly patients with chronic kidney disease (CKD) in order to provide preventive strategies for RCS. Methods Clinical data of 222 elderly patients with CKD admitted in Chinese PLA General Hospital from March 2010 to March 2013 were collected and retrospectively analyzed. Logistic regression analysis was used to study the related risk factors of RCS. Results The incidence of RCS was 25.2% in this cohort. Univariate analysis showed that age, renal function stage, history of diabetes, hypertension, anemia, and malnutrition were related with the occurrence of RCS, while sex, smoking, history of cerebrovascular disease, duration of CKD, dyslipidemia and other factors had no obvious correlation with RCS (P>0.05). Multivariate logistic regression analysis showed that, age, renal function stage, diabetes, hypertension, and anemia were independent risk factors for RCS. Conclusion CKD patients with advanced age (≥80 years), advanced renal dysfunction (≥stage 3B), diabetes, hypertension and anemia are of high risk of RCS. Therefore, special attention should be paid to the evaluation and control of above-mentioned risk factors.