CAJ | 학술논문

目的：探讨磁共振弥散加权成像(DWI)联合颅颈血管造影(MRA)在短暂性脑缺血发作(TIA)中的临床应用价值。方法：选择经临床和影像学确诊TIA患者72例为TIA组，均在发病1周内行颅脑DWI和颅颈部MRA检查；随机选择同期健康体检者36名为正常组，对两组进行对比。结果：TIA组与正常组在颅颈动脉狭窄程度和狭窄数量上具有显著性差异(t=12.316，P<0.01)。TIA组颅颈动脉狭窄及闭塞增多。椎基底动脉TIA患者单侧椎动脉发育不良比例增高。TIA患者DWI上均未见新鲜缺血灶，6例病情进展患者DWI上出现高信号，诊断为脑梗死。结论：颅脑DWI是鉴别TIA及脑梗死的简单有效检查手段，而MRA可明确颅颈动脉狭窄位置及严重程度， DWI联合MRA对TIA患者的病因诊断及其继发脑梗死的风险评估具有重大临床价值。
목적：탐토자공진미산가권성상(DWI)연합로경혈관조영(MRA)재단잠성뇌결혈발작(TIA)중적림상응용개치。방법：선택경림상화영상학학진TIA환자72례위TIA조，균재발병1주내행로뇌DWI화로경부MRA검사；수궤선택동기건강체검자36명위정상조，대량조진행대비。결과：TIA조여정상조재로경동맥협착정도화협착수량상구유현저성차이(t=12.316，P<0.01)。TIA조로경동맥협착급폐새증다。추기저동맥TIA환자단측추동맥발육불량비례증고。TIA환자DWI상균미견신선결혈조，6례병정진전환자DWI상출현고신호，진단위뇌경사。결론：로뇌DWI시감별TIA급뇌경사적간단유효검사수단，이MRA가명학로경동맥협착위치급엄중정도， DWI연합MRA대TIA환자적병인진단급기계발뇌경사적풍험평고구유중대림상개치。
Objective:To study the value in clinical application of diffusion weighted imagine (DWI) and magnetic resonance angiography (MRA) in transient ischemic attacks (TIA). Methods:A totle of 72 patients diagnose as TIA by clinical manifestation and medical imaging, Brain DWI and brain and carotid MRA were underwent in the disease within a week. 36 healthy checkup people were randomly chosen as control subjects. The differences of sex and age of two groups have no statistical significance (P>0.05). Results:There were significant differences among the two groups in the degree and the number of stenosis of cranial and cervical arteries (t=12.316, P<0.01). The stenosis and occlusion of arteries were severe in the patients with TIA than that in healthy adults. The incidence of dysplasia of unilateral vertebral arteries (VA) in TIA was higher than that in the normal subjects. the patients with TIA don’t all display fresh focal ischemia on DWI. 6 case patients of disease progression happen cerebral infarction display abnormally high signal on DWI. Conclusion:Brain DWI is an simply and effective way to identify TIA and cerebral infarction. MRA can show the location and the degree of stenosis of cranial and cervical arteries. DWI combined MRA has great value for etiological diagnosis of TIA and the risk assessment of cerebral infarction.