CAJ | 학술논문

目的了解支气管激发试验阳性患者对14种吸入变应原（过敏原）过敏的分布状况和相关性。方法选取366例支气管激发试验阳性患者进行变应原皮试。结果366例患者中297例对14种变应原试验阳性，总阳性率为81.1％；过敏原以屋尘、粉尘螨、多价昆虫、春季花粉Ⅰ等为主；其中对6种及6种以上变应原过敏的患者占35.7％。皮试阳性组患者与皮试阴性组患者吸入使第一秒用力呼气容积（ FEV1）下降20％的乙酰甲胆碱累积剂量（ PD20 FEV1）差异有统计学意义（ P＜0.05）。结论支气管激发试验阳性患者最常见的过敏原为屋尘、粉尘螨、多价昆虫、春季花粉Ⅰ等；PD20FEV1与变应原皮试检出阳性率可能存在相关性。
목적료해지기관격발시험양성환자대14충흡입변응원（과민원）과민적분포상황화상관성。방법선취366례지기관격발시험양성환자진행변응원피시。결과366례환자중297례대14충변응원시험양성，총양성솔위81.1％；과민원이옥진、분진만、다개곤충、춘계화분Ⅰ등위주；기중대6충급6충이상변응원과민적환자점35.7％。피시양성조환자여피시음성조환자흡입사제일초용력호기용적（ FEV1）하강20％적을선갑담감루적제량（ PD20 FEV1）차이유통계학의의（ P＜0.05）。결론지기관격발시험양성환자최상견적과민원위옥진、분진만、다개곤충、춘계화분Ⅰ등；PD20FEV1여변응원피시검출양성솔가능존재상관성。
Objective To investigate the distribution and relevance of 14 inhaled allergens in the patients with positive results of bronchial provocation test .Methods The allergen skin test was performed in 366 selected pa-tients with positive results of bronchial provocation test .Results Two hundred and ninety-seven cases were positive for 14 kinds of allergens , with a total positive rate of 81.1%.35.7%of the patients were allergic to 6 or more kinds of the allergens .Mainly allergens were house dust , dermatophagoides , multivalent insects , and spring pollen Ⅰ.The difference on cumulative inhaled dose of methacholine resulted 20% fall in FEV1 ( PD20FEV1 ) between the positive and negative results on the skin test was statistically significant ( P<0.05 ) .Conclusion The most common aller-gens of patients with positive results of bronchial provocation test were house dust , dermatophagoides , multivalent in-sects, and spring pollen Ⅰ.PD20FEV1 is probaly correlated to the positive rate of allergen skin test .