CAJ | 학술논문

以β-环糊精为壁材，以包埋率为指标，采用单因素试验和Box-Behnken 中心组合设计试验对超声法制备苯甲酸钠微胶囊的工艺进行优化。试验结果表明：超声法制备苯甲酸钠包合物的最佳工艺条件为芯/壁材比1∶7．17，超声包埋时间29．9 min，超声包埋功率180 W，此条件下的实际包埋率为80．5％，与模型预测值之间具有较好的拟合性。
이β-배호정위벽재，이포매솔위지표，채용단인소시험화Box-Behnken 중심조합설계시험대초성법제비분갑산납미효낭적공예진행우화。시험결과표명：초성법제비분갑산납포합물적최가공예조건위심/벽재비1∶7．17，초성포매시간29．9 min，초성포매공솔180 W，차조건하적실제포매솔위80．5％，여모형예측치지간구유교호적의합성。
Takeβ-cyclodextrin as wall material and embedding rate of sodium benzoate as main index, the single factor experiment and Box-Behnken response surface methodology for optimization of sodi-um benzoate microcapsules by ultrasound method is explored.The results show that the optimum process conditions for preparation of sodium benzoate clathrate by ultrasound method are as follows:the core/wall material ratio of 1∶7.17,the ultrasonic embedding time of 29.9 min,the ultrasonic embedding power of 180 W,the embedding rate can reach 80.5%,and the regression model is con-sistent with the predicted results.