实用癌症杂志
實用癌癥雜誌
실용암증잡지
THE PRACTICAL JOURNAL OF CANCER
2014年
2期
165-167
,共3页
晚期非小细胞肺癌%化疗%预后%COX回归分析
晚期非小細胞肺癌%化療%預後%COX迴歸分析
만기비소세포폐암%화료%예후%COX회귀분석
Advanced non-small cell lung cancer%Chemotherapy%Prognosis%COX regression analysis
目的:探讨影响晚期非小细胞肺癌化疗预后的独立因素。方法回顾性分析168例行化疗的晚期非小细胞肺癌患者的临床资料,分别采用单因素分析和多因素分析方法对其预后因素进行分析。结果168例患者化疗后生存时间为5~77个月,中位生存时间为13.1个月,1、3、5年生存率分别为56.1%、40.2%、29.7%。单因素分析结果显示临床分期、KPS评分、化疗药物、化疗周期及化疗效果是影响患者预后的相关因素;多因素分析显示临床分期、KPS评分及化疗效果是影响预后的独立相关因素。结论临床分期、KPS评分及化疗疗效,是晚期非小细胞肺癌患者化疗后的独立预后因素。
目的:探討影響晚期非小細胞肺癌化療預後的獨立因素。方法迴顧性分析168例行化療的晚期非小細胞肺癌患者的臨床資料,分彆採用單因素分析和多因素分析方法對其預後因素進行分析。結果168例患者化療後生存時間為5~77箇月,中位生存時間為13.1箇月,1、3、5年生存率分彆為56.1%、40.2%、29.7%。單因素分析結果顯示臨床分期、KPS評分、化療藥物、化療週期及化療效果是影響患者預後的相關因素;多因素分析顯示臨床分期、KPS評分及化療效果是影響預後的獨立相關因素。結論臨床分期、KPS評分及化療療效,是晚期非小細胞肺癌患者化療後的獨立預後因素。
목적:탐토영향만기비소세포폐암화료예후적독립인소。방법회고성분석168례행화료적만기비소세포폐암환자적림상자료,분별채용단인소분석화다인소분석방법대기예후인소진행분석。결과168례환자화료후생존시간위5~77개월,중위생존시간위13.1개월,1、3、5년생존솔분별위56.1%、40.2%、29.7%。단인소분석결과현시림상분기、KPS평분、화료약물、화료주기급화료효과시영향환자예후적상관인소;다인소분석현시림상분기、KPS평분급화료효과시영향예후적독립상관인소。결론림상분기、KPS평분급화료료효,시만기비소세포폐암환자화료후적독립예후인소。
Objective To explore the independent prognostic factors of advanced non-small cell lung cancer ( NSCLC) patients after chemotherapy .Methods Clinical data of 168 advanced NSCLC patients after chemotherapy were retrospectively an-alyzed.The univariate analysis and the multivariate analysis were used to analyze the prognostic factors .Results The survival time was 5 77 months.The median survival time was 13.1months.The 1-year,3-year and 5-year survival rate were 56.1% and 40.2%and 29.7%,respectively.The univariate analysis suggested that TNM staging ,KPS scoring,chemotherapy regimen,chem-otherapy cycles and chemotherapy effect were related prognostic factors .Multivariate analysis suggested that TNM staging , KPS scoring and chemotherapy effect were related independent prognostic factors .Conclusion TNM staging,KPS scoring,and chemo-therapy effect are the independent prognostic factors of advanced NSCLC patients treated with chemotherapy .