CAJ | 학술논문

目的：探讨影响晚期非小细胞肺癌化疗预后的独立因素。方法回顾性分析168例行化疗的晚期非小细胞肺癌患者的临床资料，分别采用单因素分析和多因素分析方法对其预后因素进行分析。结果168例患者化疗后生存时间为5～77个月，中位生存时间为13．1个月，1、3、5年生存率分别为56．1％、40．2％、29．7％。单因素分析结果显示临床分期、KPS评分、化疗药物、化疗周期及化疗效果是影响患者预后的相关因素；多因素分析显示临床分期、KPS评分及化疗效果是影响预后的独立相关因素。结论临床分期、KPS评分及化疗疗效，是晚期非小细胞肺癌患者化疗后的独立预后因素。
목적：탐토영향만기비소세포폐암화료예후적독립인소。방법회고성분석168례행화료적만기비소세포폐암환자적림상자료，분별채용단인소분석화다인소분석방법대기예후인소진행분석。결과168례환자화료후생존시간위5～77개월，중위생존시간위13．1개월，1、3、5년생존솔분별위56．1％、40．2％、29．7％。단인소분석결과현시림상분기、KPS평분、화료약물、화료주기급화료효과시영향환자예후적상관인소；다인소분석현시림상분기、KPS평분급화료효과시영향예후적독립상관인소。결론림상분기、KPS평분급화료료효，시만기비소세포폐암환자화료후적독립예후인소。
Objective To explore the independent prognostic factors of advanced non-small cell lung cancer ( NSCLC) patients after chemotherapy .Methods Clinical data of 168 advanced NSCLC patients after chemotherapy were retrospectively an-alyzed.The univariate analysis and the multivariate analysis were used to analyze the prognostic factors .Results The survival time was 5 77 months.The median survival time was 13.1months.The 1-year,3-year and 5-year survival rate were 56.1% and 40.2%and 29.7%,respectively.The univariate analysis suggested that TNM staging ,KPS scoring,chemotherapy regimen,chem-otherapy cycles and chemotherapy effect were related prognostic factors .Multivariate analysis suggested that TNM staging , KPS scoring and chemotherapy effect were related independent prognostic factors .Conclusion TNM staging,KPS scoring,and chemo-therapy effect are the independent prognostic factors of advanced NSCLC patients treated with chemotherapy .