CAJ | 학술논문

目的：检测β细胞素（BTC）在肝癌组织及癌旁组织中的表达并探讨其与肝癌侵袭能力的相关性。方法：采用免疫组织化学法检测BTC在肝癌组织和癌旁组织中的表达水平。结果：BTC在肝癌组织中的表达与癌旁组织相比存在高表达的现象，且肿瘤直径≥3cm和有包膜浸润的肝癌组织中BTC也存在高表达的现象，而且这些差异有统计学意义（P＜0．05）。结论：BTC表达与肝癌的增殖、侵袭能力密切相关，可能在肝癌发生、发展过程中起着重要的作用。
목적：검측β세포소（BTC）재간암조직급암방조직중적표체병탐토기여간암침습능력적상관성。방법：채용면역조직화학법검측BTC재간암조직화암방조직중적표체수평。결과：BTC재간암조직중적표체여암방조직상비존재고표체적현상，차종류직경≥3cm화유포막침윤적간암조직중BTC야존재고표체적현상，이차저사차이유통계학의의（P＜0．05）。결론：BTC표체여간암적증식、침습능력밀절상관，가능재간암발생、발전과정중기착중요적작용。
Objective:To investigate the BTC protein expression in hepatocellular carcinoma tissue and tissue around the lesion and to analyze its related clinical factors .Methods :To detect the BTC protein expression by immunohistochemistry .Results :BTC protein expression in HCC tissue is higher than it in tissue around the lesion , and its protein expression is higher in the lesion whose diameter is bigger than 3cm and which shows capsular inva-sion .Conclusion:BTC expression is closely associated with the proliferation and invasion of HCC ,it may play an im-portant role in the generation and development of HCC .