CAJ | 학술논문

由于抗生素耐药病原菌的出现，一些传染性疾病已难以治疗并且日益恶化。近年来开发新的和有效的抗生素进展缓慢。然而，可替代抗生素的细菌素近些年来备受关注，其在控制抗生素耐药病原菌上拥有巨大的潜力。细菌素是由许多细菌产生的小抗菌肽（ AMPs），不仅可以有效地抑制病原体生长，还可以作为益生菌在医疗中发挥重要作用。同时，细菌素作为防腐剂在食品生产中普遍应用，随着人们对畜产品卫生与安全的关注以及益生菌在饲料中的推广应用，细菌素在动物生产中也有着非常广阔的应用前景。为此，本文旨在在介绍细菌素的概念、分类、作用机制的基础上，进一步介绍细菌素在动物生产上的应用。
유우항생소내약병원균적출현，일사전염성질병이난이치료병차일익악화。근년래개발신적화유효적항생소진전완만。연이，가체대항생소적세균소근사년래비수관주，기재공제항생소내약병원균상옹유거대적잠력。세균소시유허다세균산생적소항균태（ AMPs），불부가이유효지억제병원체생장，환가이작위익생균재의료중발휘중요작용。동시，세균소작위방부제재식품생산중보편응용，수착인문대축산품위생여안전적관주이급익생균재사료중적추엄응용，세균소재동물생산중야유착비상엄활적응용전경。위차，본문지재재개소세균소적개념、분류、작용궤제적기출상，진일보개소세균소재동물생산상적응용。
Due to the emergence of antibiotic-resistant pathogens, some infectious diseases are difficult to treat and are getting worse.In recent years, the development of new and effective antibiotics is slow.However, the alternative antibiotics bacteria are concerned in recent years, which have a great potential to inhibit antibiotic-resistant pathogens by bacteriocins.Bacteriocins are small antimicrobial peptides ( AMPS) which are produced by many bacteria, they not only can inhibit effectively pathogen growth, but also can play an important role in health care as probiotics.At the same time, bacteriocins have been commonly used as a preservative in food production.With the focus on health and safety of livestock products as well as popularization and application of probiotics in diet increasing, bacteriocins will be widely used in animal production.This review summarizes the concept, classification, mechanism of bacteriocins, and discusses present research progress about the appli-cation of bacteriocins in animal production.