中国中医药信息杂志
中國中醫藥信息雜誌
중국중의약신식잡지
CHINESE JOURNAL OF INFORMATION ON TRADITIONAL CHINESE MEDICINE
2014年
3期
81-83
,共3页
降糖通络颗粒%正交试验%提取工艺%芍药苷
降糖通絡顆粒%正交試驗%提取工藝%芍藥苷
강당통락과립%정교시험%제취공예%작약감
Jiangtang Tongluo Granule%orthogonal test%extraction process%paeoniflorin
目的：优选降糖通络颗粒的最佳提取工艺。方法采用正交试验法，以加水量、提取次数、提取时间为因素，出膏率和芍药苷含量为考察指标，采用高效液相色谱法对芍药苷含量进行检测，以确定最佳提取工艺。结果降糖通络颗粒的最佳的提取工艺为：药材加10倍量水，煎煮3次，每次1 h。结论该工艺条件合理，稳定可行，为该制剂的生产和质量控制奠定了基础。
目的：優選降糖通絡顆粒的最佳提取工藝。方法採用正交試驗法，以加水量、提取次數、提取時間為因素，齣膏率和芍藥苷含量為攷察指標，採用高效液相色譜法對芍藥苷含量進行檢測，以確定最佳提取工藝。結果降糖通絡顆粒的最佳的提取工藝為：藥材加10倍量水，煎煮3次，每次1 h。結論該工藝條件閤理，穩定可行，為該製劑的生產和質量控製奠定瞭基礎。
목적：우선강당통락과립적최가제취공예。방법채용정교시험법，이가수량、제취차수、제취시간위인소，출고솔화작약감함량위고찰지표，채용고효액상색보법대작약감함량진행검측，이학정최가제취공예。결과강당통락과립적최가적제취공예위：약재가10배량수，전자3차，매차1 h。결론해공예조건합리，은정가행，위해제제적생산화질량공제전정료기출。
Objective To investigate the optimal extraction process of Jiangtang Tongluo Granule. Methods The orthogonal design was used in the extraction, according to the yield rate and content of paeoniflorin, with the volume of water, extraction times and extraction time as factors. The content of paeoniflorin was detected by HPLC method to determine the best extraction technology. Results The optimal water extracting technology of Jiangtang Tongluo Granule was performed by 1 h extraction for 3 times, with 10-fold volume of water. Conclusion The process is stable, feasible and reasonable, and provides a foundation for the further production and quality control.
