中国中医药信息杂志
中國中醫藥信息雜誌
중국중의약신식잡지
CHINESE JOURNAL OF INFORMATION ON TRADITIONAL CHINESE MEDICINE
2014年
3期
62-64
,共3页
金龙胶囊%氨基酸%指纹图谱%超高液相色谱法
金龍膠囊%氨基痠%指紋圖譜%超高液相色譜法
금룡효낭%안기산%지문도보%초고액상색보법
Jinlong capsule%amino acid%fingerprint%UPLC
目的：建立金龙胶囊氨基酸类成分指纹图谱。方法采用6-氨基喹啉基-N-羟基琥珀酰亚氨基甲酸酯(AQC)进行柱前衍生化,超高效液相色谱法同时测定制剂中17种氨基酸,建立金龙胶囊氨基酸类成分指纹图谱。结果共标出22个共有峰,鉴定出17种氨基酸,10批样品相似度均＞0.9。结论所建立的金龙胶囊氨基酸类成分指纹图谱特征性强,可以作为金龙胶囊质量控制的手段之一。
目的：建立金龍膠囊氨基痠類成分指紋圖譜。方法採用6-氨基喹啉基-N-羥基琥珀酰亞氨基甲痠酯(AQC)進行柱前衍生化,超高效液相色譜法同時測定製劑中17種氨基痠,建立金龍膠囊氨基痠類成分指紋圖譜。結果共標齣22箇共有峰,鑒定齣17種氨基痠,10批樣品相似度均＞0.9。結論所建立的金龍膠囊氨基痠類成分指紋圖譜特徵性彊,可以作為金龍膠囊質量控製的手段之一。
목적：건립금룡효낭안기산류성분지문도보。방법채용6-안기규람기-N-간기호박선아안기갑산지(AQC)진행주전연생화,초고효액상색보법동시측정제제중17충안기산,건립금룡효낭안기산류성분지문도보。결과공표출22개공유봉,감정출17충안기산,10비양품상사도균＞0.9。결론소건립적금룡효낭안기산류성분지문도보특정성강,가이작위금룡효낭질량공제적수단지일。
Objective To establish the fingerprint of amino acids composition of Jinlong capsule. Methods Using 6-acetamido-4-hydroxy-2-methyl quinoline (AQC) as the derivating agent, 17 kinds of amino acids were analyzed by UPLC at the same time and the fingerprint of amino acids composition of Jinlong capsule was established. Result Totally 22 co-possessing peaks were selected as the fingerprint peaks, 17 kinds of amino acids were identified. The fingerprint similarity value of 10 batches was above 0.9. Conclusion The fingerprint is characteristic and can be used for the quality control of Jinlong capsule.
