CAJ | 학술논문

目的：总结乳管镜（fiberoptic ductoscopy，FDS）治疗乳管内病变临床应用经验。方法：回顾性分析中南大学湘雅三医院近10年来使用FDS检查的1368例乳头溢液病例的临床资料。结果：不同性状的溢液FDS诊断有着显著的差异，血性和浆液性溢液组肿瘤性疾病检出率明显高于水样和乳汁样溢液组；对于非肿瘤性乳头溢液，FDS下灌洗治疗能取得较好的治疗效果；FDS定位下手术组较传统切除手术组，FDS诊断病理符合率更高（χ2=10.56，P=0.001）。结论：FDS不仅是诊断乳头溢液病因的可靠方法，而且可以对非肿瘤性乳头溢液进行有效的灌洗治疗；对于肿瘤性疾病引起的乳头溢液，FDS下定位切除手术能够避免手术盲目性，为病灶的切除提供可靠的帮助。
목적：총결유관경（fiberoptic ductoscopy，FDS）치료유관내병변림상응용경험。방법：회고성분석중남대학상아삼의원근10년래사용FDS검사적1368례유두일액병례적림상자료。결과：불동성상적일액FDS진단유착현저적차이，혈성화장액성일액조종류성질병검출솔명현고우수양화유즙양일액조；대우비종류성유두일액，FDS하관세치료능취득교호적치료효과；FDS정위하수술조교전통절제수술조，FDS진단병리부합솔경고（χ2=10.56，P=0.001）。결론：FDS불부시진단유두일액병인적가고방법，이차가이대비종류성유두일액진행유효적관세치료；대우종류성질병인기적유두일액，FDS하정위절제수술능구피면수술맹목성，위병조적절제제공가고적방조。
Objective:To consolidate ten years of clinical experience on the application of breast fiberoptic ductoscopy (FDS) in breast intra-ductal lesion. Methods:The clinical data of 1 368 cases of patients with nipple discharge were retrospectively collected and analyzed. Results:Significant differences were observed in the FDS diagnoses of patients with nipple discharge. The rates of tumor de-tection by FDS diagnosis were significantly higher when bloody and serous nipple discharge was used rather than milky and watery nip-ple discharge. For non-tumor nipple discharge, local drug perfusion via FDS was an effective treatment. A total of 303 patients had tu-mor resection or segmentectomy under localization via FDS, and 44 had segmentectomy after breast duct infusion of methylene blue. The diagnostic rate of localization via FDS (97.0%) was higher than that of breast duct infusion of methylene blue (86.4%). Conclu-sion:FDS is an accurate method for diagnosing patients with nipple discharge. In addition, it is also a good local drug perfusion method for patients with breast inflammatory nipple discharge ductoscopy. For patients with tumorous nipple discharge, localization via FDS can help improve the detection of the lesions, which can be removed by surgery.