CAJ | 학술논문

目的：探讨输血前不规则血型抗体筛查对提高临床输血安全的意义。方法对2000例预输血患者进行抗体筛查，对不规则抗体筛查阳性的标本进行抗体特异性鉴定，统计不规则抗体的特异性和检出率。结果共筛出不规则抗体阳性者8例，阳性检出率为0．4％。其中血液系统疾病和肿瘤患者6例，占75．0％，高于其他疾病患者所占比例（2例，25．0％），比较差异有统计学意义（P＜0．05）。不规则抗体阳性患者抗体特异性鉴定结果显示， Rh系统抗体占62．5％，MNS系统抗体（抗-M抗体）占37．5％。结论输血前对患者进行不规则抗体检测，有利于选择适合患者的血液，有效减少或避免溶血性输血反应的发生，保证了患者的输血安全。
목적：탐토수혈전불규칙혈형항체사사대제고림상수혈안전적의의。방법대2000례예수혈환자진행항체사사，대불규칙항체사사양성적표본진행항체특이성감정，통계불규칙항체적특이성화검출솔。결과공사출불규칙항체양성자8례，양성검출솔위0．4％。기중혈액계통질병화종류환자6례，점75．0％，고우기타질병환자소점비례（2례，25．0％），비교차이유통계학의의（P＜0．05）。불규칙항체양성환자항체특이성감정결과현시， Rh계통항체점62．5％，MNS계통항체（항-M항체）점37．5％。결론수혈전대환자진행불규칙항체검측，유리우선택괄합환자적혈액，유효감소혹피면용혈성수혈반응적발생，보증료환자적수혈안전。
Objective To investigate the value of irregular antibody screening in clinical blood transfusion. Methods 2 000 pre-transfusion patients underwent antibody screening were enrolled.Antibody specificity identifica-tion was performed for positive irregular specimens.Irregular antibody specificity and incidence were recorded.Re-sults There were 8 cases positive with irregular antibody,the positive rate was 0.4%,among which there were 6 patients with blood system diseases and tumors,accounting for 75.0%,higher than the proportion of patients with other diseases (2 cases,25.0%),and the difference was statistically significant (P<0.05).Irregular antibody speci-ficity identification indicated that Rh system antibodies accounted for 62.5%,and MNS system antibody (anti-M an-tibody)accounted for 37.5%.Conclusion Irregular antibody screening before blood transfusion might be helpful for choosing blood fit for patients,reducing or avoiding the occurrence of hemolytic transfusion reaction,and ensuing the safety of blood transfusion.