CAJ | 학술논문

目的：观察激素在治疗合并2型糖尿病的重度或极重度突发性聋患者的疗效，以及将血糖控制在不同水平下使用激素的疗效，以指导临床实践。方法试验一使用相同降糖药物将患者空腹及3餐后2 h血糖控制在7.8～13.9 mmol/L，对比在使用其他共同治疗方案前提下使用和不使用激素治疗合并2型糖尿病的重度或极重度突发性聋患者疗效差异。试验二各组患者均使用其他共同治疗方案+激素治疗，使用相同降糖药物将患者空腹及3餐后2h血糖控制在不同水平，观察患者疗效差异。结果在将患者空腹及3餐后2 h血糖控制在7.8～13.9 mmol/L条件下，在除其他共同治疗方案外另使用激素治疗疗效好于不使用激素者。在同样使用共同治疗方案和激素治疗，将患者空腹及3餐后2 h血糖控制在不同水平，患者治疗疗效不同。不能认为血糖控制在13.9 mmol/L以下的两种不同血糖水平使用激素治疗疗效有显著差异。但血糖控制在13.9 mmol/L以下使用激素治疗疗效好于血糖控制在13.9 mmol/L以上的患者。结论在合并2型糖尿病的重度或极重度突发性聋患者治疗时早期使用激素可提高疗效；在激素治疗中，同时注意控制血糖，血糖需控制在一定范围之内，可无需控制到正常水平。
목적：관찰격소재치료합병2형당뇨병적중도혹겁중도돌발성롱환자적료효，이급장혈당공제재불동수평하사용격소적료효，이지도림상실천。방법시험일사용상동강당약물장환자공복급3찬후2 h혈당공제재7.8～13.9 mmol/L，대비재사용기타공동치료방안전제하사용화불사용격소치료합병2형당뇨병적중도혹겁중도돌발성롱환자료효차이。시험이각조환자균사용기타공동치료방안+격소치료，사용상동강당약물장환자공복급3찬후2h혈당공제재불동수평，관찰환자료효차이。결과재장환자공복급3찬후2 h혈당공제재7.8～13.9 mmol/L조건하，재제기타공동치료방안외령사용격소치료료효호우불사용격소자。재동양사용공동치료방안화격소치료，장환자공복급3찬후2 h혈당공제재불동수평，환자치료료효불동。불능인위혈당공제재13.9 mmol/L이하적량충불동혈당수평사용격소치료료효유현저차이。단혈당공제재13.9 mmol/L이하사용격소치료료효호우혈당공제재13.9 mmol/L이상적환자。결론재합병2형당뇨병적중도혹겁중도돌발성롱환자치료시조기사용격소가제고료효；재격소치료중，동시주의공제혈당，혈당수공제재일정범위지내，가무수공제도정상수평。
Objective: In type 2 diabetes with severe or very severe in patients with sudden hearingloss, observed hormone therapy,as wel as dif erent levels of blood glucose under control to observe the ef ect of hormone use, to guide clinical practice. Methods: Test one: Using the same glucose-lowering drugs wil patients fasting blood sugar and meals 2 hours after blood glucose control in 7.8 ~ 13.9 mmol/L, in the use of other common treatments premise, compared to use, or not to use hormone treatment of type 2 diabetes with sudden hearingloss (severe or extremely severe) patients dif erences. Test two:Each patient al use other common treatments + hormone therapy, using the same of hypoglycemic agents in patients with fasting glucose and 2 hours after meals blood sugar control in dif erent levels, observes the patient curative ef ect dif erence. Results: In the fasting and 2 hours after meals blood glucose control in the 7.8 ~ 13.9mmol / L conditions, in addition to other common treatment programs, alternative use of hormone therapy more ef ective than those who do not use hormones. Use the same common treatment and hormone therapy, patient empty stomach blood sugar and meal lat er 2 hour blood sugar control in dif erent level, therapy in patients with dif erent. In blood glucose control in 13.9mmol / L fol owing two dif erent blood sugar levels, hormone therapy can not be considered a significant dif erence. However, blood glucose control in 13.9mmol / L the fol owing use of hormone therapy is ef ective in blood sugar control in 13.9mmol / L or more of patients. Conclusion: In type 2 diabetes with severe or very severe patients with sudden hearingloss treatment early use of hormones may improve the outcome; in hormone therapy, with at ention to control of blood glucose, blood glucose should be control ed in a certain range, can be no control to normal level.