CAJ | 학술논문

目的：观察两种不同白内障手术方式对角膜内皮细胞的影响。方法：选择2011-03/10在我院眼科行白内障手术的年龄相关性白内障患者82例82眼，随机分为超声乳化手术组（A组）与小切口白内障囊外摘除手术组（B组）。观察两组在手术前后不同阶段的角膜内皮细胞变化及术后角膜水肿情况。结果：（1）术后7d时两组角膜内皮细胞平均密度均较术前降低（P＜0．05），数值随时间略有增长，但至术后3mo时仍低于相应术前水平（P＜0．05）；术后7d；1，3mo时角膜内皮细胞平均密度A组明显高于B组（P＜0．05）；（2）两组术后7d；1，3mo的六角形细胞比例均值较各组术前低，组间存在差异（P＜0．05）；（3）术后角膜水肿情况A组较B组轻（P＜0．05）。结论：超声乳化手术相对小切口白内障囊外摘除手术对于角膜内皮的损伤要轻，术后角膜水肿发生率要低。
목적：관찰량충불동백내장수술방식대각막내피세포적영향。방법：선택2011-03/10재아원안과행백내장수술적년령상관성백내장환자82례82안，수궤분위초성유화수술조（A조）여소절구백내장낭외적제수술조（B조）。관찰량조재수술전후불동계단적각막내피세포변화급술후각막수종정황。결과：（1）술후7d시량조각막내피세포평균밀도균교술전강저（P＜0．05），수치수시간략유증장，단지술후3mo시잉저우상응술전수평（P＜0．05）；술후7d；1，3mo시각막내피세포평균밀도A조명현고우B조（P＜0．05）；（2）량조술후7d；1，3mo적륙각형세포비례균치교각조술전저，조간존재차이（P＜0．05）；（3）술후각막수종정황A조교B조경（P＜0．05）。결론：초성유화수술상대소절구백내장낭외적제수술대우각막내피적손상요경，술후각막수종발생솔요저。
AIM: To compare the effects of small incision extracapsular cataract extraction and phacoemulsification on corneal endothelial cells. METHODS: Eighty-two age-related cataract cases ( 82 eyes) from March 2011 to October 2011, were randomly divided into two groups: phacoemulsification group ( group A ) and small incision extracapsular cataract extraction group ( group B ) . Corneal edema after operation and changes in corneal endothelial cells in different stages before and after operation were observed. RESULTS: In both groups, there was significant difference in the data of corneal endothelial cell density before and after operation ( P<0.05 ).Although all the postoperative data of corneal endothelial cell density were lower than the preoperative ones, they had been slightly increasing over time. The mean density of corneal endothelial cell in group A was significantly higher than that in group B at 7d, 1 month and 3 months after operation ( P <0.05 ). In both groups, the average proportion of corneal hexagonal cells at 7d, 1 month and 3 months after operation was obviously lower than that before surgery, with significant difference between the two groups.Postoperative corneal edema was less severe in group A than in group B (P<0.05). CONCLUSION:Phacoemulsification causes less damage to corneal endothelial cells and less postoperative corneal edema than small incision extracapsular cataract extraction.