国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2013年
11期
2192-2195
,共4页
邓军萍%江威%邵毅%孙伍花%胡虹%杨青
鄧軍萍%江威%邵毅%孫伍花%鬍虹%楊青
산군평%강위%소의%손오화%호홍%양청
密蒙花%视力%中医证候%单纯性糖尿病视网膜病变
密矇花%視力%中醫證候%單純性糖尿病視網膜病變
밀몽화%시력%중의증후%단순성당뇨병시망막병변
Buddleja officinalis%vision%traditional chinese medcine symptoms%simple diabetic retinopathy
目的：观察密蒙花联合复方血栓通胶囊治疗轻、中度单纯性糖尿病视网膜病变的临床效果。方法：2型糖尿病并发轻、中度单纯性糖尿病性视网膜病变患者80例160眼，在严格控制血糖及血压基础上随机分为A、B两组，A组使用口服密蒙花加用口服复方血栓通胶囊治疗，B组口服复方血栓通胶囊，分别在治疗前和治疗后7，42 d后观察视力、眼底镜检查、眼底荧光血管造影、眼底照相及中医症候的变化。结果：两组比较患者性别、年龄、DM病程、视力、DR 病情、病程及中医症候情况均无显著性差异（χ2性别＝0．472， P＞0．05；t年龄＝1．742，tDM病程＝0．716，t视力＝0．662，tDR病情＝1．276，tDR病程＝0．562，t中医症候积分＝0．616，P均＞0．05）。平均随访42d，A组眼底病变治疗有效率为56％，总有效率82％；B组显效率32％，总有效率66％，结果显示A组疗效优于B组，两组有效率比较有统计学意义（χ2＝8.025， P＜0．05）。 A组中医证候显效率50％，总有效率80％；B组显效率24％，总有效率62％，结果显示A组中医证候优于B组，两组有效率比较有统计学意义（χ2＝5．980，P＜0．05）。结论：密蒙花联合复方血栓通胶囊可改善轻、中度单纯性糖尿病视网膜病变患者视力，眼底病变及中医证候，具有一定的临床意义。
目的：觀察密矇花聯閤複方血栓通膠囊治療輕、中度單純性糖尿病視網膜病變的臨床效果。方法：2型糖尿病併髮輕、中度單純性糖尿病性視網膜病變患者80例160眼，在嚴格控製血糖及血壓基礎上隨機分為A、B兩組，A組使用口服密矇花加用口服複方血栓通膠囊治療，B組口服複方血栓通膠囊，分彆在治療前和治療後7，42 d後觀察視力、眼底鏡檢查、眼底熒光血管造影、眼底照相及中醫癥候的變化。結果：兩組比較患者性彆、年齡、DM病程、視力、DR 病情、病程及中醫癥候情況均無顯著性差異（χ2性彆＝0．472， P＞0．05；t年齡＝1．742，tDM病程＝0．716，t視力＝0．662，tDR病情＝1．276，tDR病程＝0．562，t中醫癥候積分＝0．616，P均＞0．05）。平均隨訪42d，A組眼底病變治療有效率為56％，總有效率82％；B組顯效率32％，總有效率66％，結果顯示A組療效優于B組，兩組有效率比較有統計學意義（χ2＝8.025， P＜0．05）。 A組中醫證候顯效率50％，總有效率80％；B組顯效率24％，總有效率62％，結果顯示A組中醫證候優于B組，兩組有效率比較有統計學意義（χ2＝5．980，P＜0．05）。結論：密矇花聯閤複方血栓通膠囊可改善輕、中度單純性糖尿病視網膜病變患者視力，眼底病變及中醫證候，具有一定的臨床意義。
목적：관찰밀몽화연합복방혈전통효낭치료경、중도단순성당뇨병시망막병변적림상효과。방법：2형당뇨병병발경、중도단순성당뇨병성시망막병변환자80례160안，재엄격공제혈당급혈압기출상수궤분위A、B량조，A조사용구복밀몽화가용구복복방혈전통효낭치료，B조구복복방혈전통효낭，분별재치료전화치료후7，42 d후관찰시력、안저경검사、안저형광혈관조영、안저조상급중의증후적변화。결과：량조비교환자성별、년령、DM병정、시력、DR 병정、병정급중의증후정황균무현저성차이（χ2성별＝0．472， P＞0．05；t년령＝1．742，tDM병정＝0．716，t시력＝0．662，tDR병정＝1．276，tDR병정＝0．562，t중의증후적분＝0．616，P균＞0．05）。평균수방42d，A조안저병변치료유효솔위56％，총유효솔82％；B조현효솔32％，총유효솔66％，결과현시A조료효우우B조，량조유효솔비교유통계학의의（χ2＝8.025， P＜0．05）。 A조중의증후현효솔50％，총유효솔80％；B조현효솔24％，총유효솔62％，결과현시A조중의증후우우B조，량조유효솔비교유통계학의의（χ2＝5．980，P＜0．05）。결론：밀몽화연합복방혈전통효낭가개선경、중도단순성당뇨병시망막병변환자시력，안저병변급중의증후，구유일정적림상의의。
AIM: To observe the clinical effect of Buddleja officinalis and Xueshuangtong capsule treating the mild and moderate simple diabetic retinopathy ( sDR) . METHODS: Based on the strict control of blood glucose and blood pressure, eighty patients (160 eyes) with mild and moderate sDR were randomized into two groups equally: Buddleja officinalis ( 15g, tid ) and Xueshuangtong capsule administered to group A and only Xueshuangtong capsule administered to group B. They are taken before meals half an hour.The vision, funduscopy, FFA, fundus photography and traditional chinese medcine symptoms ( TCMS ) were evalutated before and after treatment in 7d,42 d respectively. RESULTS: There were no significant difference between two groups in terms of patients'gender, age, DM course, visual acuity, course of disease and TCM syndrome.(χ2sex=0.472, P>0.05; tage=1.742,tDM condition=0.716,tvision=0.662,tDR degree=1.276,tDR condition=0.562,t TCM S=0.616, P >0.05 );Follow up for 42d on average after treatment the effective rate of fundus lesions of group A was 56%and the total effective rate was 82%, while the effective rate of group B was 32% and the total effective rate was 66%.The result showed that the curative effect of group A was better than that of group B.There were statistically significant difference for the effective rate between the two groups (χ2 =8.025, P<0.05 ).The effective rate of TCMS in group A was 50%, and total effective rate was 80%, while group B shows a 24%effective rate and 62% total effective ratet.The result showed that the curative effect of group A was significantly better than that of group B (χ2=5.980,P<0.05). CONCLUSION:Buddleja officinalis and Xueshuangtong capsule can improve the vision of patients with the mild and moderate sDR patients, the fundus lesions and the TCMS.
