CAJ | 학술논문

目的观察近视眼LASIK手术后相对调节的变化情况.方法临床病例对照研究.对2010年3～6月在广州医学院第一附属医院眼科就诊的年龄在18～40岁拟行LASIK手术的近视患者64例(128只眼),按近视程度分为:轻中度近视组(＜-6.0 D)和高度近视组(≥-6.0 D);同时根据年龄分成年轻组(＜30岁)和年长组(≥30岁),统一行标准的LASIK手术,分别于术前与术后1周、1个月及3个月行负与正相对调节检查.统计采用重复测量的方差分析法比较手术前及术后3个时期相对调节的差异,对两不同组别间的比较采用独立样本的t检验.结果负相对调节:不同屈光度组手术前后各时期的负相对调节差异无统计学意义(P =0.565,0.117,P＞0.05);不同年龄组手术前后各时期的负相对调节差异无统计学意义(P =0.074,0.237,P＞0.05).正相对调节:轻中度近视组和高度近视组手术前后正相对调节差异有统计学意义(P =0.000,0.000,P＜0.05);两个年龄组手术前后正相对调节差异有统计学意义(P =0.000,0.000,P＜0.05).不同屈光度及年龄组均表现为术后1周正相对调节较术前下降差异有统计学意义(P均＜0.05),术后1个月逐渐恢复至术前水平差异无统计学意义(P均＞0.05),术后3个月高度近视组正相对调节均较术前升高,差异有统计学意义(P均＜0.05).结论 LASIK手术对近视眼的调节功能有一定影响,近视眼术后正相对调节早期呈一过性降低,1个月后可逐渐恢复或增强.
목적 관찰근시안LASIK수술후상대조절적변화정황.방법 림상병례대조연구.대2010년3～6월재엄주의학원제일부속의원안과취진적년령재18～40세의행LASIK수술적근시환자64례(128지안),안근시정도분위:경중도근시조(＜-6.0 D)화고도근시조(≥-6.0 D);동시근거년령분성년경조(＜30세)화년장조(≥30세),통일행표준적LASIK수술,분별우술전여술후1주、1개월급3개월행부여정상대조절검사.통계채용중복측량적방차분석법비교수술전급술후3개시기상대조절적차이,대량불동조별간적비교채용독립양본적t검험.결과 부상대조절:불동굴광도조수술전후각시기적부상대조절차이무통계학의의(P =0.565,0.117,P＞0.05);불동년령조수술전후각시기적부상대조절차이무통계학의의(P =0.074,0.237,P＞0.05).정상대조절:경중도근시조화고도근시조수술전후정상대조절차이유통계학의의(P =0.000,0.000,P＜0.05);량개년령조수술전후정상대조절차이유통계학의의(P =0.000,0.000,P＜0.05).불동굴광도급년령조균표현위술후1주정상대조절교술전하강차이유통계학의의(P균＜0.05),술후1개월축점회복지술전수평차이무통계학의의(P균＞0.05),술후3개월고도근시조정상대조절균교술전승고,차이유통계학의의(P균＜0.05).결론 LASIK수술대근시안적조절공능유일정영향,근시안술후정상대조절조기정일과성강저,1개월후가축점회복혹증강.
Objective To investigate the changes in relative accommodation after laser in situ keratomileusis (LASIK) for myopia.Methods Sixty-four myopic patients (128 eyes) who were going to receive standard LASIK were enrolled in this study with the age from 18 to 40 years and were divided into two groups:low to moderate myopic group (＞-6.0D),and high myopic group (≤ -6.0D).According to the age,the patients also were categorized into two groups:＜30 years and ≥ 30 years.Negative and positive relative accommodation was measured before surgery and 1 week,1 month and 3 months after surgery.Results Negative relative accommodation (NRA):There was no significant difference in NRA in all groups between before and after surgery (all P ＞0.05).Positive relative accommodation (PRA):The mean PRA was decreased significantly in all groups at 1 week after LASIK (all P ＜0.05),and recovered to preoperative level at one month after LASIK (all P ＞ 0.05).The PRA was significantly increased in high myopic group at 3 months after surgery compared with pre-operation (all P ＜0.05).Conclusions The positive accommodation decreases in the early weeks after LASIK for myopia,and maybe it is the reason why some patients have difficulty for near work after LASIK.