医学理论与实践
醫學理論與實踐
의학이론여실천
The Journal of Medical Theory and Practice
2013年
20期
2676-2677
,共2页
谢冬梅%廖述霞%罗双红%杨林
謝鼕梅%廖述霞%囉雙紅%楊林
사동매%료술하%라쌍홍%양림
新生儿黄疸%金双歧%蓝光照射%疗效
新生兒黃疸%金雙歧%藍光照射%療效
신생인황달%금쌍기%람광조사%료효
Neonatal jaundice%Jinshuangqi%Blu-ray irradiation%Efficacy
目的：观察金双歧联合蓝光照射治疗新生儿黄疸的临床疗效，指导临床合理治疗。方法：将100例新生儿高胆红素血症按随机数字表分为观察组50例和对照组50例，对照组采用常规方法联合蓝光照射治疗，观察组在对照组的基础在口服金双歧，两组均治疗5d ，观察治疗前、后症状改善情况，检测血清胆红素及粪胆素水平，评判两组临床疗效。结果：（1）观察组和对照组的总有效率分别为96％和74％，χ2＝11．027，P＜0．01；（2）观察组和对照组的首次排胎粪时间、胎粪排净时间、黄疸消退时间分别为（2．1±0．4）h比（6．4±1．5）h，（4．9±0．8）h比（10．5±4．3）h，（4．4±1.2）h比（7．8±2．2）h ，均 P＜0．01；（3）治疗后观察组和对照组血清胆红素与粪胆素分别为（46．4±15．5）μmol/L比（93．6±23．3）μmol/L ，（166．1±41．6）mg/100g比（113．3±31．8）mg/100g ，均 P＜0．01。结论：金双歧联合蓝光照射治疗新生儿黄疸能加快症状消除，降低血清胆红素水平，促进胆红素最终变为粪胆素，减少胆红素肝肠循环，明显缩短治疗时间，且安全性良好，具有较好的临床应用价值。
目的：觀察金雙歧聯閤藍光照射治療新生兒黃疸的臨床療效，指導臨床閤理治療。方法：將100例新生兒高膽紅素血癥按隨機數字錶分為觀察組50例和對照組50例，對照組採用常規方法聯閤藍光照射治療，觀察組在對照組的基礎在口服金雙歧，兩組均治療5d ，觀察治療前、後癥狀改善情況，檢測血清膽紅素及糞膽素水平，評判兩組臨床療效。結果：（1）觀察組和對照組的總有效率分彆為96％和74％，χ2＝11．027，P＜0．01；（2）觀察組和對照組的首次排胎糞時間、胎糞排淨時間、黃疸消退時間分彆為（2．1±0．4）h比（6．4±1．5）h，（4．9±0．8）h比（10．5±4．3）h，（4．4±1.2）h比（7．8±2．2）h ，均 P＜0．01；（3）治療後觀察組和對照組血清膽紅素與糞膽素分彆為（46．4±15．5）μmol/L比（93．6±23．3）μmol/L ，（166．1±41．6）mg/100g比（113．3±31．8）mg/100g ，均 P＜0．01。結論：金雙歧聯閤藍光照射治療新生兒黃疸能加快癥狀消除，降低血清膽紅素水平，促進膽紅素最終變為糞膽素，減少膽紅素肝腸循環，明顯縮短治療時間，且安全性良好，具有較好的臨床應用價值。
목적：관찰금쌍기연합람광조사치료신생인황달적림상료효，지도림상합리치료。방법：장100례신생인고담홍소혈증안수궤수자표분위관찰조50례화대조조50례，대조조채용상규방법연합람광조사치료，관찰조재대조조적기출재구복금쌍기，량조균치료5d ，관찰치료전、후증상개선정황，검측혈청담홍소급분담소수평，평판량조림상료효。결과：（1）관찰조화대조조적총유효솔분별위96％화74％，χ2＝11．027，P＜0．01；（2）관찰조화대조조적수차배태분시간、태분배정시간、황달소퇴시간분별위（2．1±0．4）h비（6．4±1．5）h，（4．9±0．8）h비（10．5±4．3）h，（4．4±1.2）h비（7．8±2．2）h ，균 P＜0．01；（3）치료후관찰조화대조조혈청담홍소여분담소분별위（46．4±15．5）μmol/L비（93．6±23．3）μmol/L ，（166．1±41．6）mg/100g비（113．3±31．8）mg/100g ，균 P＜0．01。결론：금쌍기연합람광조사치료신생인황달능가쾌증상소제，강저혈청담홍소수평，촉진담홍소최종변위분담소，감소담홍소간장순배，명현축단치료시간，차안전성량호，구유교호적림상응용개치。
Objective :To observe the effect of Jinshuangqi and Blu-ray irradiation in the treatment of neonatal jaun-dice ,to guide clinical treatment .Methods :100 neonatal hyperbilirubinemia were randomly divided into observation group and control group ,50 cases of each group ,control group were given conventional methods and Blu-ray irradiation ,ob-servation group were given Jinshuangqi on base on control group ,both had been treated for 5d ,observed symptoms ,de-tected Serum bilirubin and Fecal bile pigment ,evaluated clinical efficacy .Results:(1) The total effective rate of obser-vation group and control group were 96% VS 74% ,χ2 =11 .027 ,P<0 .01 ;(2)the time of first pass meconium ,meconi-um drain and jaundice disappearance of observation group and control group were (2 .1 ± 0 .4)h VS (6 .4 ± 1 .5)h , (4 .9 ± 0 .8)h VS (10 .5 ± 4 .3)h ,(4 .4 ± 1 .2)h VS (7 .8 ± 2 .2)h ,all P<0 .01 ;(3) after treatment Serum bilirubin and Fecal bile pigment of observation group and control group were (46 .4 ± 15 .5)μmol/L VS (93 .6 ± 23 .3)μmol/L , (166.1 ± 41 .6)mg/100g VS (113 .3 ± 31 .8)mg/100g ,all P< 0 .01 .Conclusion:The method contained Jinshuangqi with Blu-ray irradiation can speed up the elimination of symptoms ,lower serum bilirubin levels ,promote bilirubin be-came fecal bile pigment ,reduce enterohepatic circulation of bilirubin ,shorter treatment time ,and the security is good , has better clinical value .
