CAJ | 학술논문

目的：分析Evan′s综合征患者输血前的血清学试验结果，探讨该类患者的输血策略。方法根据患者红细胞直接抗球蛋白分型试验结果，选择热放散或氯喹放散法，将放散后的红细胞进行ABO和Rh血型定型，并与自身血清进行吸收试验。热放散液或吸收处理后的血清进行抗体筛选和鉴定试验。根据抗体鉴定结果选择合适的血液，分别采用盐水法、聚凝胺法、LISS/Coomb′s凝胶卡法进行主侧交叉配血试验；对比患者输血前后的血红蛋白，以判定输血效果。结果患者血型均得到正确定型；检出抗-E2例、抗-S1例，1例抗体特异性未明确；交叉配血结果相合，输血效果理想。结论 Evan′s综合征患者的血清学试验相对复杂，应当综合分析；要重视血液选择策略，避免出现输血反应。
목적：분석Evan′s종합정환자수혈전적혈청학시험결과，탐토해류환자적수혈책략。방법근거환자홍세포직접항구단백분형시험결과，선택열방산혹록규방산법，장방산후적홍세포진행ABO화Rh혈형정형，병여자신혈청진행흡수시험。열방산액혹흡수처리후적혈청진행항체사선화감정시험。근거항체감정결과선택합괄적혈액，분별채용염수법、취응알법、LISS/Coomb′s응효잡법진행주측교차배혈시험；대비환자수혈전후적혈홍단백，이판정수혈효과。결과환자혈형균득도정학정형；검출항-E2례、항-S1례，1례항체특이성미명학；교차배혈결과상합，수혈효과이상。결론 Evan′s종합정환자적혈청학시험상대복잡，응당종합분석；요중시혈액선택책략，피면출현수혈반응。
Objective To analyze the Evan′s syndrome patients′ serum tests results ,and discuss the strategy for transfusion .Methods Patients′RBC was dealt with heat elution or chloroquine elution according to the direct an-tiglobulin test results .The RBC was divided equally for two parts after elution test ,one was used to test the ABO and Rh group ,and the other was used to absorpt with autoserum .Irregular antibody was screened and identified with elu-ant or the serum after absorption test .Homotype blood was chosen for cross match blood test in saline ,polybrene and LISS/Coomb′s card .Results All patients′ blood was tested correctly .Antibody-like E was identified in two cases , antibody S was identified in one case ,and one patient′s antibody specificity was not identified .Blood cross match blood test was negative .Conclusion Correct serum tests are complicated for Evan syndrome patient ,and strategy for transfusion should be emphasized to avoid transfusion reaction .