CAJ | 학술논문

目的：探讨急性脑梗死中医证型与血清IL-1在近期感染中的相关性。方法：选取2010年1月-2013年1月笔者所在医院接收的急性脑梗死患者152例，分为观察组和对照组，各76例，测定急性心肌梗死患者外周血IL-1的含量，对比IL-1在不同症候中的水平。结果：(1)观察组患者外周血中IL-1含量明显高于对照组(P<0.05)；(2)72 h内火热证组IL-1水平均明显高于非火热证组(P<0.05)，第7、14天IL-1水平无显著性差异；(3)观察组火热证中，72 h内与第7、14天IL-1含量比较差异有统计学意义(P<0.05)，非火热证中无显著性差异。结论：外周血IL-1升高可能成为脑梗死患者急性期感染程度的指标之一，同时也可能成为判定急性脑梗死火热证与非火证的参考指标之一。
목적：탐토급성뇌경사중의증형여혈청IL-1재근기감염중적상관성。방법：선취2010년1월-2013년1월필자소재의원접수적급성뇌경사환자152례，분위관찰조화대조조，각76례，측정급성심기경사환자외주혈IL-1적함량，대비IL-1재불동증후중적수평。결과：(1)관찰조환자외주혈중IL-1함량명현고우대조조(P<0.05)；(2)72 h내화열증조IL-1수평균명현고우비화열증조(P<0.05)，제7、14천IL-1수평무현저성차이；(3)관찰조화열증중，72 h내여제7、14천IL-1함량비교차이유통계학의의(P<0.05)，비화열증중무현저성차이。결론：외주혈IL-1승고가능성위뇌경사환자급성기감염정도적지표지일，동시야가능성위판정급성뇌경사화열증여비화증적삼고지표지일。
Objective:To study the TCM Syndromes of acute cerebral infarction and serum IL-1 in the near future infection correlation.Method:Selecting 152 cases from 2010 January to 2013 January in our hospital received patients with acute cerebral infarction,they were divided into the observation group 76 cases and control group 76 cases,content determination in patients with acute myocardial infarction and peripheral blood IL-1,compared with IL-1 in different syndrome in the horizontal.Result:The content of IL-1 in peripheral blood from patients with observation was significantly higher than that of control group(P<0.05), in the 72 hour fireheat syndrome group IL-1 levels were significantly higher than those in non heat syndrome group(P<0.05),the 7,14 d,IL-1 was no significant differencewas observed in the group of heat syndrome,72 hours and seventh days,fourteenth days IL-1 content had significant difference(P<0.05),there was no significant difference in non heat syndrome.Conclusion:The increase of IL-1 in peripheral blood may be one of the indexes in patients with acute cerebral infarction in the degree of infection,also may be one of the reference index of the acute cerebral infarction fire and non fire syndromes.