CAJ | 학술논문

实验小鼠模型逐渐被应用于各个领域，尤其是转基因和基因敲除小鼠在心血管疾病方面的研究更是与日俱增。心脏磁共振(CMR)成像技术为无创性检查心脏的解剖和功能、心肌灌注以及心肌活性提供了方便。对于实验小鼠CMR技术而言，因小鼠自身特点的特殊性，在磁共振扫描设备、成像线圈、实验动物的准备和监测、心脏成像序列以及磁共振成像的分析和后处理等这些方面，都必须进行相关的调整和研究。本文将从上述几个方面综述近年来实验小鼠CMR技术的最新进展。
실험소서모형축점피응용우각개영역，우기시전기인화기인고제소서재심혈관질병방면적연구경시여일구증。심장자공진(CMR)성상기술위무창성검사심장적해부화공능、심기관주이급심기활성제공료방편。대우실험소서CMR기술이언，인소서자신특점적특수성，재자공진소묘설비、성상선권、실험동물적준비화감측、심장성상서렬이급자공진성상적분석화후처리등저사방면，도필수진행상관적조정화연구。본문장종상술궤개방면종술근년래실험소서CMR기술적최신진전。
Experimental mice models have been gradually used in various fields, especially transgenic and knockout mice in cardiovascular disease. Cardiac magnetic resonance (CMR) could provide noninvasive, high resolution images of heart anatomy, viability, perfusion and function. Further research of mice CMR technology should be performed, due to the special features of the mice as well as special MRI equipment, coil, mice preparation and monitoring, image analysis and post-processing. Latest progress of mice CMR in technology will be reviewed in this article.