CAJ | 학술논문

以 PEG/IPDI/DMPA 为原料,通过溶液聚合法,获得了嵌段离聚体溶液(溶剂为 N,N-二甲基甲酰胺),然后在水相界面上对疏水功能性有机分子DCOIT进行自组装包覆制备DCOIT纳米胶囊。实验最终通过FT-IR、表面张力测试表征了嵌段离聚体的结构及性能,粒径分布和冷冻切片 TEM和紫外-可见分光光度计对DCOIT纳米胶囊的形貌和释放特性进行了研究。研究结果表明,实验制备出了预期结构的聚氨酯嵌段离聚体,并形成了 DCOIT 纳米胶囊；DCOIT纳米胶囊的释放特性表现为,当壁芯比在1∶1至2∶1之间变化时,纳米胶囊都在释放初期速率较快,然后经历一个减速期,随后速率再次增加；且随着壁芯比的减小,DCOIT 纳米胶囊的减速期越来越短。最后,对DCOIT 纳米胶囊的释放机理进行了初步探讨。
이 PEG/IPDI/DMPA 위원료,통과용액취합법,획득료감단리취체용액(용제위 N,N-이갑기갑선알),연후재수상계면상대소수공능성유궤분자DCOIT진행자조장포복제비DCOIT납미효낭。실험최종통과FT-IR、표면장력측시표정료감단리취체적결구급성능,립경분포화냉동절편 TEM화자외-가견분광광도계대DCOIT납미효낭적형모화석방특성진행료연구。연구결과표명,실험제비출료예기결구적취안지감단리취체,병형성료 DCOIT 납미효낭；DCOIT납미효낭적석방특성표현위,당벽심비재1∶1지2∶1지간변화시,납미효낭도재석방초기속솔교쾌,연후경력일개감속기,수후속솔재차증가；차수착벽심비적감소,DCOIT 납미효낭적감속기월래월단。최후,대DCOIT 납미효낭적석방궤리진행료초보탐토。
Self-assembly coated DCOIT nanocasules were synthesized by block ionomer solution,in which the solution was prepared by solution polymerization reaction using PEG/IPDI/DMPA (N,N-dimethylformamide was the solvent).The physicochemical properties of the block ionomer synthesized and the particle size,mor-phology and optical properties of the DCOIT nanocasules prepared were characterized with particle size analy-zer,transmission electron microscopy (TEM)and UV-Vis spectrometer.The results of this study showed that the block polyurethane and DCOIT nanocasules were prepared successfully.As the ratio of wall/core varied from 1∶1 to 2∶1 ,the release rate of the nanocapsules was fast at first,and then experienced a deceleration stage,after that,it increased sharply.The deceleration stage became shorter as the ratio decrease.Finally,the release mechanism of DCOIT nanocapsules was discussed.