CAJ | 학술논문

目的：探讨脑利钠肽对新生儿心力衰竭早期诊断的临床意义。方法选择2011年1月~2013年6月在本院新生儿科确诊为新生儿心力衰竭的>3 d的患儿36例为观察组,同期收治的未合并心力衰竭的新生儿30例为对照组,测定两组患儿治疗前的BNP浓度和观察组治疗7 d后的BNP浓度,分别比较两组治疗前BNP浓度、观察组治疗前后的BNP浓度及对照组和观察组治疗后BNP浓度。结果观察组治疗前的值明显高于对照组和观察组治疗后的值,P<0.05,差异有统计学意义,观察组治疗后的值与对照组比较, P>0.05,差异无统计学意义。结论BNP水平的动态变化可反应新生儿心力衰竭的恢复情况,可作为早期发现新生儿心力衰竭的检测指标。
목적：탐토뇌리납태대신생인심력쇠갈조기진단적림상의의。방법선택2011년1월~2013년6월재본원신생인과학진위신생인심력쇠갈적>3 d적환인36례위관찰조,동기수치적미합병심력쇠갈적신생인30례위대조조,측정량조환인치료전적BNP농도화관찰조치료7 d후적BNP농도,분별비교량조치료전BNP농도、관찰조치료전후적BNP농도급대조조화관찰조치료후BNP농도。결과관찰조치료전적치명현고우대조조화관찰조치료후적치,P<0.05,차이유통계학의의,관찰조치료후적치여대조조비교, P>0.05,차이무통계학의의。결론BNP수평적동태변화가반응신생인심력쇠갈적회복정황,가작위조기발현신생인심력쇠갈적검측지표。
Objective To discuss the clinical significance of brain natriuretic peptide(BNP) in early diagnosing the cardiac failure of neonate.Methods We defined the 36 newborn diagnosed cardiac failure >3 days in our unit from January 2011 to Jun 2013 as observed group, and the 30 newborn without cardiac failure as control group. We measured the BNP of the two groups before treating and the observed group after treating 7 days. The BNP of the two groups, the observed group before and after treating, the after treating and the control were compared.Results The BNP of the two groups, before and after treating of the observed group had statistical difference (P<0.01). The difference of the after treating and the control had no statistical significance (P>0.05). Conclusion The dynamic change of BNP can react the recovering of cardiac failure of the neonate, it can be a detection index to early diagnosis the cardiac failure of the newborn.